A facile synthesis of CoMn₂O₄ nanosheets on reduced graphene oxide for non-enzymatic glucose sensing

Abstract

A non-enzymatic sensor nanomaterial which is composed of ultra-thin scaly CoMn2O4 nanosheets grown on the surface of reduced graphene oxide sheets (CoMn2O4 NSs/rGO) has been successfully synthesized by a simple method for glucose sensing. The morphology and elemental composition of CoMn2O4 NSs/rGO are researched by means of x-ray diffraction, field emission scanning electron microscope, and transmission electron microscope. Cyclic voltammetry and amperometry are used to analyse the glucose oxidation characteristics of the material. The test results show that the non-enzymatic glucose sensor based on CoMn2O4 NSs/rGO has excellent glucose sensing performance, exhibiting a wide linear range of 0.1–30 mM with high sensitivity of 6830.5 μA mM−1 cm−2, which is better than other glucose sensors. In addition, the CoMn2O4 NSs/rGO sensor has superior anti-interference and stability. More importantly, the sensor can be applied to the measurement of real sample, which makes it have the potential to become a reliable clinical glucose sensor.

Synthesis of CuSe/PVP/GO and CuSe/MWCNTs for their applications as nonenzymatic electrochemical glucose biosensors

“…Notably, nanomaterials nd signicant application in manufacturing sensors for detecting biomolecules, drugs, heavy metals, facilitating early diagnosis of medical conditions, and enabling bioimaging. [16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] Diabetes, being a prevalent chronic disease affecting 1.5 million individuals globally, poses signicant health challenges, leading to complications like blindness, renal failure, and nerve degeneration. Predicted data indicates that diabetes may surpass heart disease as the seventh leading cause of death by 2030.…”

“…Composites with graphene, such as graphene-based polymer nanocomposites and graphene oxide nanocomposites decorated with various nanoparticles, have been employed by many researchers for glucose sensing. [22][23][24] Another carbon-based nano-material i.e., carbon nanotubes (CNTs), known for their excellent conductivity and high surface area, have garnered attention, especially in non-enzymatic glucose sensing when combined with metal nanoparticles. 29,[31][32][33] Copper-based nanomaterials, valued for their electrocatalytic performance, stability, and cost-effectiveness, have seen application in various composites.…”

“…Notably, nanomaterials find significant application in manufacturing sensors for detecting biomolecules, drugs, heavy metals, facilitating early diagnosis of medical conditions, and enabling bioimaging. 16–35…”

Cost Effective Synthesis of Graphene Nanomaterials for Non-Enzymatic Electrochemical Sensors for Glucose: A Comprehensive Review

“…The high potential values cause the oxidation of the Co(II) to CoOOH which is favorable for the GER in order to be preceded. Furthermore, the combination of Co with another metal oxide, e.g., CoMn 2 O 4 /rGO (0.1 M NaOH), may offer more hydroxide species, leading to a multi-step and more complex GER mechanism [ 24 ]: …”

Preparation of Non-Enzymatic Glucose Sensing Nanocomposite Based on NiCo₂O₄ Nanosheets@ Reduced Graphene Oxide and Design of Glucose Detection System

“…Among them, the cost of precious metal is high. Although the cost of transition metal oxides is low, their conductivity is poor [6,7]. In contrast, the conductivity of binary transition metal oxides is significantly improved.…”