A feasibility study of different GSI noise indexes and concentrations of contrast medium in hepatic CT angiography of overweight patients: image quality, radiation dose, and iodine intake

Zhao, Sai; Liu, Zhichao; Zhao, Yongxia; Zhang, Tianle; Zuo, Zhentao

doi:10.1007/s11604-022-01384-w

Cited by 4 publications

(2 citation statements)

References 24 publications

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“…Since a One-Size-Fits-All method to scan all patients was technically inappropriate, different noise indices were used in our study for the Auto-kVp group. According to Zhao et al's study [25], NI was increased to 15 for patients whose BMI ≥ 24 kg/m 2 in hepatic CTA. Although NI could be increased even larger to achieve a considerable dose reduction[26], the image quality would be heavily deteriorated, such as affecting the delineation of colorectal tumor and the margin sharpness, which led to low subjective scores.…”

Section: Discussionmentioning

confidence: 97%

Achieving sub-milliSievert CT colonography for accurate colorectal tumor detection using smart examination protocols: a prospective self-controlled study

Zhang,

Hu,

Cheng

et al. 2024

Preprint

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Purpose To assess the feasibility of combining Auto-kVp selection technique, higher preset ASIR-V and noise index (NI) to realize individualized sub-mSv CT colonography (CTC) for accurate colorectal tumor detection and localization. Methods Ninety patients with suspected colorectal cancer (CRC) were prospectively enrolled to undergo standard dose CTC (SDCTC) in the prone and ultra-low dose CTC (ULDCTC) in the supine position. SDCTC used 120 kVp, preset ASIR-V of 30%, SmartmA for a NI of 13; ULDCTC used Auto-kVp selection technique with 80 or 100 kVp, preset ASIR-V of 60%, SmartmA for a NI of 13 for 80 kVp, and NI of 15 for 100 kVp. The effective dose (ED), image quality [signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of colorectal neoplasms] between the two protocols were compared and the accuracies of tumor locations were evaluated for CTC in comparison with the surgery results. Results The mean ED of the 80 kVp subgroup was 0.70mSv, 71.43% lower than the 2.45mSv for the 120kVp group, while that of the 100 kVp subgroup was 0.98mSv, 73.00% lower than the 3.63mSv for the 120 kVp group (P < 0.001). The tumor SNR and CNR of the ULDCTC were higher than those of SDCTC (P < 0.05), while there was no difference in the subjective image quality between them with good inter-observer agreement (Kappa: 0.805–0.923). Both SDCTC and ULDCTC groups had high detection rate of colorectal tumors, along with good consistency in determining tumor location compared with surgery reports (Kappa: 0.718–0.989). Conclusion The combination of Auto-kVp selection, higher preset ASIR-V and NI achieves individualized sub-mSv CTC with good performance in detecting and locating CRC with surgery and consistent results between SDCTC and ULDCTC.

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Section: Discussionmentioning

confidence: 97%

Achieving sub-milliSievert CT colonography for accurate colorectal tumor detection using smart examination protocols: a prospective self-controlled study

Zhang,

Hu,

Cheng

et al. 2024

Preprint

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“…However, a contrast-enhanced chest CT protocol with fewer phases will be needed to reduce radiation exposure in the future, and methods to predict the optimal scan timing of CTA-P and CTA-S for each case are necessary. Based on the findings of this study, more optimized scanning protocols with reduced contrast load and radiation dose can be realized in the future by combining low-concentration contrast agents with the latest imaging techniques such as dual-energy CT and photon-counting CT [ 24 , 25 ].…”

Section: Discussionmentioning

confidence: 99%

Serial assessment of computed tomography angiography for pulmonary and systemic arteries using a reduced contrast agent dose for the diagnosis of systemic artery-to-pulmonary artery shunts

Fukamatsu,

Yamada,

Yamada

et al. 2023

Jpn J Radiol

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Purpose To evaluate the diagnostic performance and feasibility of a modified computed tomography (CT) scan protocol, we performed a serial assessment of the computed tomography angiography for pulmonary artery (CTA-P) and systemic artery (CTA-S) (CTA-PS) using a reduced contrast agent dose to diagnose systemic artery-to-pulmonary artery shunts (SPSs). Materials and methods Twenty-five patients who underwent multiphase contrast-enhanced chest CT and conventional chest angiography were included. Three image sets (CTA-P, CTA-S, and CTA-PS) were evaluated by two board-certified radiologists. The visualization of the CT image findings associated with SPSs, such as filling defects and enhancement in the pulmonary arteries, was evaluated using a 5-point scale. Results The diagnostic performance (sensitivity, specificity, and accuracy) of CT imaging findings associated with SPSs in CTA-P and CTA-PS were as follows: CTA-P, 57.1%, 87.5%, and 62.0%; CTA-PS, 81.0%, 100.0%, and 84.0%. CT findings associated with SPSs in CTA-P were significantly sensitive to the CTA-PS protocol. There were no significant differences between the CTA-S and CTA-PS protocols. The area under the curve (AUC) of the CT imaging findings associated with SPSs in the CTA-P and CTA-PS groups was 0.835 and 0.911, respectively (P = 0.191). The AUC of the CT imaging findings associated with SPSs in CTA-S and CTA-PS were 0.891 and 0.926, respectively (P = 0.373). Conclusion CTA-PS using a reduced contrast agent dose protocol could improve the overall diagnostic confidence of SPSs, owing to better visualization of CT imaging findings associated with SPSs compared to individual assessments of CTA-P or CTA-S. Therefore, CTA-PS can be used as an alternative preembolization evaluation modality to conventional angiography in patients with hemoptysis suspected of having SPSs.

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Achieving sub-millisievert CT colonography for accurate colorectal tumor detection using smart examination protocols: a prospective self-controlled study

Zhang,

Hu,

Cheng

et al. 2024

Abdom Radiol

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A feasibility study of different GSI noise indexes and concentrations of contrast medium in hepatic CT angiography of overweight patients: image quality, radiation dose, and iodine intake

Cited by 4 publications

References 24 publications

Achieving sub-milliSievert CT colonography for accurate colorectal tumor detection using smart examination protocols: a prospective self-controlled study

Achieving sub-milliSievert CT colonography for accurate colorectal tumor detection using smart examination protocols: a prospective self-controlled study

Serial assessment of computed tomography angiography for pulmonary and systemic arteries using a reduced contrast agent dose for the diagnosis of systemic artery-to-pulmonary artery shunts

Achieving sub-millisievert CT colonography for accurate colorectal tumor detection using smart examination protocols: a prospective self-controlled study

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