A first study on nanoporous tungsten recording electrodes for deep brain stimulation

Shuang, Fei; Deng, Haokun; Shafique, Ashfaque Bin; Marsh, Stephen; Treiman, David M.; Tsakalis, K.; Aifantis, Katerina E.

doi:10.1016/j.matlet.2019.126885

Cited by 9 publications

(8 citation statements)

References 13 publications

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“…It has been shown the electrodes with nanoporous substrates have the ability to reduce impedance and increase conductivity as compared with the smoother electrodes. A similar study reported by Shuang et al demonstrated that Tungsten electrodes with nanoporous features showed reduced signal attenuations indicating enhanced consistency as compared with the smother electrodes [ 137 ]. These studies further suggests that the nanoporous materials have greater applications in bioelectronics space, since they have the potential to exhibit excellent electrochemical properties, biocompatibility, and stability [ 138 ].…”

Section: Biomedical Applications Of Nanoporous Materialsmentioning

confidence: 63%

Recent Advancements in the Fabrication of Functional Nanoporous Materials and Their Biomedical Applications

et al. 2022

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Functional nanoporous materials are categorized as an important class of nanostructured materials because of their tunable porosity and pore geometry (size, shape, and distribution) and their unique chemical and physical properties as compared with other nanostructures and bulk counterparts. Progress in developing a broad spectrum of nanoporous materials has accelerated their use for extensive applications in catalysis, sensing, separation, and environmental, energy, and biomedical areas. The purpose of this review is to provide recent advances in synthesis strategies for designing ordered or hierarchical nanoporous materials of tunable porosity and complex architectures. Furthermore, we briefly highlight working principles, potential pitfalls, experimental challenges, and limitations associated with nanoporous material fabrication strategies. Finally, we give a forward look at how digitally controlled additive manufacturing may overcome existing obstacles to guide the design and development of next-generation nanoporous materials with predefined properties for industrial manufacturing and applications.

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Section: Biomedical Applications Of Nanoporous Materialsmentioning

confidence: 63%

Recent Advancements in the Fabrication of Functional Nanoporous Materials and Their Biomedical Applications

et al. 2022

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“…81 In vitro porous platinum electrodes have lower impedance than smooth platinum electrodes. 82 Moreover, Aifantis et al 83 implemented a nanoporous tungsten electrode for signal recording in the cerebral cortex and hippocampus of healthy rats. Compared with smooth electrodes, it was revealed that nanoporous tungsten had superior consistency and less signal attenuation within 4 months of implantation.…”

Section: Current Developing Status Of Neural Electrodesmentioning

confidence: 99%

Strategies for interface issues and challenges of neural electrodes

Liang

Yan

et al. 2022

Nanoscale

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“…Different metal wires have been used, including tungsten (W) (Shuang et al, 2020), platinum (Pt) (Rose and Robblee, 1990;Wei et al, 2015), platinum/iridium (PtIr) (Zheng, 2017;Obaid et al, 2020) and titanium (Ti) (McCarthy et al, 2011). Tungsten electrodes enabled the first recording of electrical activity from individual neurons in cat brain, which later led to Nobel Prize winning work expanding our understanding of the visual cortex (Hubel and Wiesel, 1962).…”

Section: Carbon-based Microfibers For Neural Interfacingmentioning

confidence: 99%

“…While the Young's modulus of brain tissue is below 15 kPa, silicon-based arrays and metal electrodes show much larger Young's modulus which are in the range of 107-390 GPa (Woeppel et al, 2017). The mechanical mismatch between the electrodes and brain tissue leads to stress at the electrode/tissue interface and induces the chronic inflammatory response (Shuang et al, 2020). In contrast, many carbon-based materials are softer, with smaller Young's modulus, such as 11.2 GPa in liquid crystal graphene oxide (LCGO) fibers (Xu and Gao, 2015).…”

Section: Minimal Tissue Responsementioning

confidence: 99%

Advances in Carbon-Based Microfiber Electrodes for Neural Interfacing

et al. 2021

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Neural interfacing devices using penetrating microelectrode arrays have emerged as an important tool in both neuroscience research and medical applications. These implantable microelectrode arrays enable communication between man-made devices and the nervous system by detecting and/or evoking neuronal activities. Recent years have seen rapid development of electrodes fabricated using flexible, ultrathin carbon-based microfibers. Compared to electrodes fabricated using rigid materials and larger cross-sections, these microfiber electrodes have been shown to reduce foreign body responses after implantation, with improved signal-to-noise ratio for neural recording and enhanced resolution for neural stimulation. Here, we review recent progress of carbon-based microfiber electrodes in terms of material composition and fabrication technology. The remaining challenges and future directions for development of these arrays will also be discussed. Overall, these microfiber electrodes are expected to improve the longevity and reliability of neural interfacing devices.

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A first study on nanoporous tungsten recording electrodes for deep brain stimulation

Cited by 9 publications

References 13 publications

Recent Advancements in the Fabrication of Functional Nanoporous Materials and Their Biomedical Applications

Recent Advancements in the Fabrication of Functional Nanoporous Materials and Their Biomedical Applications

Strategies for interface issues and challenges of neural electrodes

Advances in Carbon-Based Microfiber Electrodes for Neural Interfacing

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