A Five-Year Retrospective Analysis of Basal Cell Carcinoma: A Monocentric Study

Abstract

Objective: Our aim in this study is to define the histopathological subtypes, body site distribution, and incidence rates of single or multiple of BCCs. The study is conducted on patients from a single institution in Istanbul which has a migrant-receiving population reflecting that of the country overall. Method: We retrospectively analyzed data concerning 896 cases of BCC seen between 2014 and 2018. Data about patient demographics (age and sex), tumor diameter,its anatomic localization, histological type, presence of ulceration, lymphovascular/perineural invasion, and single or multiple tumor formations were retrieved from both the hospital's automated system and archived records of the pathology clinic. Results: Our univariate analysis showed that the patients' age, tumor size, and tumor multicentricity were all significantly related to their gender (p=0.011, p=0.001, and p=0.021, respectively). Further, age, male gender, and tumor size were all significantly related to tumor multicentricity (p=0.003, p=0.021, and p=0.001, respectively). BCC was most commonly found in male, and the diameters of the BCC tumors were also larger in male patients. Multiple BCC was more frequently seen in older and male patients, and the tumors had larger diameters in these groups. The nodular type of BCC was the most frequently seen type in all age groups. Conclusion: As our study is the first BCC study that has the greatest number of cases in Turkey and as Istanbul reflects the population of Turkey, it is important for the data of BCC cases in Turkey.

Epidemiological and clinicopathological analysis of basal cell carcinoma in Egyptian population: a 5-year retrospective multicenter study

“…The most common pathological BCC variant in our cohort was the nodular type which is consistent with the data reported in the literature (Cameron et al 2019 ; Tan et al 2015 ; Ozkanli et al 2020 ; Muzic et al 2017 ). Regarding the giant BCC, Vaca-Aguilera et al ( 2019 ) reported that infiltrating type was the most common pathological variant.…”

“…This could be explained in western countries by the frequent use of tanning bath by females (Kappelin et al 2022 ; Garcias-Ladaria et al 2017 ), which is not a common habit for Egyptian females due to religious and social customs. However, a Turkish study reported that females showed earlier onset of BCCs, and they share the religious customs and ethnic race with Egyptians (Ozkanli et al 2020 ).…”

“…In this study, about one third of cases were nodular non-ulcerative, and non-pigmented; while ulceration occurred in about half of lesions which is a higher proportion in comparison to the previous reports. Ozkanli et al ( 2020 ) reported ulceration in 28.6% of BCCs cases, while Yap ( 2010 ) reported ulceration in 18% of cases. This difference should be considered, as it may indicate a more progressive course of the tumor in this racial type.…”

Periocular basal cell carcinoma results and surgical outcome during a 5-year period in a larger Danish population

“…Approximately 80% of all BCC cases are diagnosed within the cervicofacial area [ 5 , 6 ]. Even though most periocular tumours are of a benign nature [ 7 ], BCC is the most frequent malignant periocular tumour and 10–16% of all BCCs are diagnosed on the eyelids [ 8 , 9 ]. Various subtypes of BCC have been described in the literature.…”