A fluorescence method for the determination of venlafaxine hydrochloride

Abstract

A novel fluorescence recovery method for the determination of venlafaxine hydrochloride was established, and used for the determination of venlafaxine hydrochloride in sustained-release tablets and capsules with satisfactory results.

A comparative study of different electrodeposited NiCo2O4 microspheres anchored on a reduced graphene oxide platform: electrochemical sensor for anti-depressant drug venlafaxine

“…The obtained results were statistically compared to those obtained by reported method. 23 The calculated t and F values at 95% condence level were less than the tabulated ones indicating that there is no signicant difference with respect to accuracy between the proposed method and the reported one. Determination of VEN in human plasma.…”

“…Also, thin layer chromatography (TLC) was described for VEN analysis in bulk and capsules. 13 Many spectrophotometric methods [14][15][16][17][18][19][20][21][22] and spectrouorimetric methods 23,24 have been reported for quantitation of VEN as well. Capillary electrophoresis was used for stereoselective analysis of VEN and its metabolites 25 and for determination of the toxic levels of VEN in human serum.…”

Simultaneous colorimetric detection of four drugs in their pharmaceutical formulations using unmodified gold nanoparticles as a probe

“…Table 1 shows the analytical data of the present method for simultaneous colorimetric detection of four drugs using unmodied Au NPs as a probe. Compared with the performance of chromatographic [7][8][9][10][11][12][13][14] and spectrophotometric [16][17][18][19] methods for detection of four drugs, the present method demonstrated a lowered detection limit and a simplied procedure (without the any sample pretreatment at minimal volume of samples) (Table 2). Although LC-MS is an efficient tool for separation and determination of four drugs independently, the unmodied Au NPs-based colorimetric method is particularly attractive for simultaneous detection of four drugs because the color changes can be easily discerned with the naked-eye and then quantied by UV-visible spectrometry, which avoids tedious sample preparations and complicated instrumentation.…”

“…[1][2][3][4][5][6] Identication and quantication of four drugs (venlafaxine; imipramine; amlodipine; alfuzosin) require a simple, specic and sensitive method for routine analysis of individual drug in biological samples. So far, various analytical techniques including high performance liquid chromatography (HPLC), [7][8][9][10] liquid chromatography with mass spectrometry (LC-MS), 14 capillary electrophoresis, 15 uorescence 16 and UV-visible spectrometry [17][18][19] have been used for the analysis of four drugs independently in pharmaceutical and biological samples. However, some of these methods are expensive, somewhat time consuming, they require derivatization steps and expensive instruments, which makes it unavailable in many laboratories for the analysis of four drugs in biological samples.…”

Bioinspired NC Coated BM‐ZIF for Electrochemical Monitoring of Adrenaline from Blood and Pharmaceutical Samples

“…But, ZIFs have a microporous shape and poor conductivity, which restricts active site exposure and mass transfer. To meet above challenges, new strategies have been designed in which ZIFs are linked with a variety of different conductive materials including multiwall carbon nanotubes [28], conducting polymers [2], and nitrogen‐carbon (NC) coated nanomaterials [29]. Among these, NC based nanomaterials offers high conductivity, ease of synthesis and modification, high temperature resistance, cheap cost, large specific surface area, chemical stability, potential to reduce electrode fouling, allowing for a rapid electron diffusion rate and enough interface contact between the modified electrode and the electrolyte and low background current [30].…”