A Focus of Sickle Cell Gene near Bombay

Haemoglobinopathies in the Indian Subcontinent.A Review of Literature

“…Sanghvi et al and Parekh respectively recorded 16 and 6 cases of S-thalassaemia in Bombay (quoted by Chatterjea 1966). Mital et al (1962) reported a high incidence of S-thalassaemia among Sorathis in Palghar (3.7%). Lele et al (1962) recorded one family of S-thalassaemia in a survey of 100 students of scheduled caste in Aurangadabad.…”

“…Sincere thanks are due to Miss Elizabeth Lowrie for excellent secretarial help. Kumar 1957Chaudhuri et al 19646 Chaudhuri et al 1967aDas et al 1967Chaudhuri et al 1963Pande et al 1970Swarup et al 1958" Lehmann et al 1961Sen 1960Pande et al 1972 BIHAR Lehmann 1954Chatterjea 1959Kirk et al 1962aPande et al 1970Pande et al 1972 GUJRAT Sukumaran et al 1956Mital et al 1962Sanghvi 1962…”

Hemoglobin Variants in India

“…The tribals from Assam show a similarly high frequency of this trait (Batabyal and Wilson 1958), though Flatz et al (1972) do not consider it to be characteristic for the autochthonous populations of Assam. Population surveys of nontribals from the same region seldom show a frequency of Hb S trait higher than 10 per cent, particularly amongst the upper castes (Bhatia et al 1955, Chaudhuri et al 1963, Kumar and Ghosh 1967, Lele et al 1962, Mital et al 1962, Sanghvi 1962, Sayed and Amin 1966, Shukla and Parande 1956, Shukla and Solanki 1958, Sukurmaran and Master 1974. Very low incidence or complete absence has been observed in some cases, e.g., in the Cutchi: in Bombay (9/599: Mehta et al 1972); in the Goans (1/379: Trincao et al 1963); in Uttar Pradesh, Maharashtra, Kerala and Andhra Pradesh (absent: Dube et al 1959, Parekh et al 1967, and Reddy and Baruah 1964; and in Bengal (1/10,000 : Chatterjea 1959).…”