A Frequency Analysis of the Regional Variation in the Contribution from Action Potentials to the Primate Multifocal ERG

Idiopathic Bilateral Optic Atrophy in the Rhesus Macaque

“…29 The changes observed for mfERG responses from the central retina of the BOA animals, specifically loss of the HFCs from these responses, are also a marker of ganglion cell dysfunction (or death). 11,12,30,31 The findings of intact low frequency components, including the N1, P1, N2, and P2 provide additional evidence that cone photoreceptor and bipolar cell function remain normal throughout the central retina in these animals. 12,32 Taken together, these electrophysiological results are consistent with loss of only ganglion cells from central retina, with relative preservation of both cone and rod photoreceptor and bipolar cell function throughout the retina.…”

Multifocal electroretinography in isolated arterially perfused bovine eye

“…These experimental models should be economical, easily available and convenient to use. Some useful data have emerged from retinal mfERG studies using live animals, including monkeys (Hood et al. , 1999; Frishman et al.…”