A functional cerebral response to frightening visual stimulation

Wik, Gustav; Fredrikson, Mais; Ericson, Kim Göransdotter; Eriksson, Lisa M J; Stone‐Elander, Sharon; Greitz, T.

doi:10.1016/0165-1781(93)80003-n

Cited by 20 publications

(18 citation statements)

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“…In studies of people with specific phobia, heightened level of SC is a common finding as a response to threat (Cook, Melamed, Cuthbert, McNeil, & Lang, 1988;Hubert & de Jong Meyer, 1990;Fredrikson et al, 1993;Wik et al, 1993;Fredrikson, Wik, Annas, Ericson, & Stone-Elander, 1995). However, in a previous study (Lundgren, Berggren, & Carlsson, 2001), we found that a control group with low dental anxiety tended towards higher SC levels than dentally anxious individuals.…”

Section: Article In Presscontrasting

confidence: 58%

Psychophysiological reactions in dental phobic patients with direct vs. indirect fear acquisition

Lundgren

Berggren

Carlsson

2004

Journal of Behavior Therapy and Experimental Psychiatry

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Section: Article In Presscontrasting

confidence: 58%

Psychophysiological reactions in dental phobic patients with direct vs. indirect fear acquisition

Lundgren

Berggren

Carlsson

2004

Journal of Behavior Therapy and Experimental Psychiatry

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“…This result is unexpected as several imaging studies have reported exaggerated amygdala responses to phobia-related pictures in SAP individuals relative to HCs [3, 4, 34]. While some studies have reported exaggerated amygdala activation in response to phobia-related stimuli, other studies did not [35–37]. Several studies have shown that the attention task demands (e.g., cognitive rating) modulate amygdala activation to emotional stimuli [38, 39].…”

Section: Discussionmentioning

confidence: 98%

Functional MRI study of specific animal phobia using an event-related emotional counting stroop paradigm

et al. 2009

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Background-Emotional interference tasks may be useful in probing anterior cingulate cortex (ACC) function to understand abnormal attentional control in individuals with specific phobia.Methods-In a 3T functional MRI scanner, individuals with specific phobias of the animal subtype (SAP, n=12) and healthy comparison adults (HC, n=12) completed an event-related emotional counting Stroop (ecStroop) task. Individuals were presented phobia-related, negative, and neutral words and were instructed to report via button-press the number of words displayed on each trial.Results-Compared to the HC group, the SAP group exhibited greater rostral ACC activation (i.e., greater response to phobia-related words than neutral words). In this same contrast, HCs exhibited greater right amygdala and posterior insula activations as well as greater thalamic deactivations than the SAP group. Both groups exhibited anterior cingulate, dorsomedial prefrontal cortex (dmPFC), inferior frontal gyrus/insula, and amygdala activations as well as thalamic deactivations. Psychophysiological interaction (PPI) analysis highlighted a network of activation in these regions in response to phobia-related words in the SAP group.Conclusions-Taken together, these findings implicate a circuit of dysfunction that is linked to attention abnormalities in individuals with SAP.

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“…The video stimulation may simply not have elicited sufficient emotional reactions. In other studies with generalized anxiety disorder patients, aviophobics, and dental phobic patients, the uses of video scenes to evoke psychophysiological reactions have been proven to be effective [11,14,16,[67][68][69][70][71][72][73], but Bornas et al [36] who used pictures instead of videos report that the addition of sound might be crucial to elicit proper physiological reactions. They found different reactions to pictures with and without sound within subsamples of flying phobics and nonphobics.…”

Section: Discussionmentioning

confidence: 99%