A general model of intake regulation

Castro, John M. de; Plunkett, Stephanie

doi:10.1016/s0149-7634(02)00018-0

Cited by 71 publications

(50 citation statements)

References 114 publications

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“…Recently, several models have been proposed to explain the set-point theory and its underlying physiological mechanisms. 28,29 According to the proposed models, differences between subjects in body mass might reflect different steady-state set-points of body mass and body fatness, which may interact with a variety of genetic and environmental factors. Under conditions of energy imbalance, whatever the mechanisms and central control systems involved, there is evidence that changes in both appetite and food intake do occur to restore body mass to its centrally encoded set-point.…”

Section: Discussionmentioning

confidence: 99%

“…Under conditions of energy imbalance, whatever the mechanisms and central control systems involved, there is evidence that changes in both appetite and food intake do occur to restore body mass to its centrally encoded set-point. Yet, some 'uncompensated factors' not influenced by intake 28,29 or a change in bodyweight set-point in the long term cannot be fully excluded. 22,30,31 To illustrate regulatory set-point, when obese subjects were below their individual set-point (e.g.…”

Section: Discussionmentioning

confidence: 99%

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Sensory-specific satiety with simple foods in humans: no influence of BMI?

Brondel

Romer²,

Wymelbeke

et al. 2006

Int J Obes

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Objective: Olfacto-gustatory sensory-specific satiety plays an important role in the termination of food ingestion. A defect in this mechanism, by increasing food intake, could be a factor in development of overweight. The present study was conducted to explore whether sensory-specific satiety in the overweight may be different from that in normal-weight subjects. Subjects: 144 subjects (half men, half women; age range: 17-62 years; BMI range: 17-39 kg m À2 ). Measurements: Olfactory pleasure (OP) and flavor pleasure (FP) were evaluated before and after ingestion of a single chosen food. Six foods from three classes were offered: cucumber and tomato, pineapple and banana, and peanut and pistachio. According to the subjects' preference for one of them, subjects were classified into six groups (24 subjects each with equal sex ratio). The experimental sequence was (1) evaluation of the six foods (OP), (2) ad libitum intake of the preferred food (FP) and (3) second evaluation of the six foods (OP). Results: Food intake was limited by sensory-specific satiety (that is, a decline in FP for the ingested food) in overweight subjects just as it was in the leanest. There was no significant correlation between BMI and hedonic parameters (OP and FP) Conclusion: After intake of a single food, olfacto-gustatory sensory-specific satiety correlated with the ingested food's weight and volume and with the duration of ingestion, but not with bodyweight. This suggests that overweight and lean subjects have similar hedonic control of food intake with simple foods.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Sensory-specific satiety with simple foods in humans: no influence of BMI?

Brondel

Romer²,

Wymelbeke

et al. 2006

Int J Obes

View full text Add to dashboard Cite

show abstract

“…The regulation of body weight is a homeostatic system that involves a negative feedback loop between intake and compensated factors (De Castro & Plunkett, 2002). Examples of compensated factors include plasma levels of blood glucose, free fatty acids, body weight, Central Nervous System (CNS) insulin, and hypothalamic neuropeptide-Y (NPY).…”

Section: Energy Intake: Body Weight and Food Consumptionmentioning

confidence: 99%

The Effects of Environmental Conditions on Activity, Feeding, and Body Weight in Male and Female Adolescent Rats

Tomchesson¹

2006

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“…It is generally suggested that this is mainly due to typical environmental factors, such as high-fat diet or lack of physical activity [31]. Without question, the common obesity phenotypes are indisputably associated with typical lifestyle and dietary characteristics that are superposed on the genetic background of an individual [10]. However, the individual response to environmental stimuli varies substantially between individuals across the population, and to the present date, little is known about the variations of the genetic factors underlying the susceptibility to specific eating behavior.…”

Section: Introductionmentioning

confidence: 99%

“…Both the meal size and meal frequency are the two traits expressing heritability [10,31]. Only a few studies have been conducted to find genes underlying this heritability.…”

Section: Introductionmentioning

confidence: 99%

Effect of ID ACE gene polymorphism on dietary composition and obesity-related anthropometric parameters in the Czech adult population

et al. 2009

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The aim of this study was to investigate the possible associations between insertion/deletion (ID) polymorphism in angiotensin-converting enzyme (ACE) (dbSNP rs 4646994) with the food intake and body composition in the Czech non-obese, obese and extremely obese populations. A total of 453 various-weighted individuals were enrolled in the study and were according to their BMI assigned into following subgroups, such as obese (30 B BMI \ 40), morbidly obese (BMI C40) and nonobese (20 \ BMI \ 30) subjects. Both the obese cases and the non-obese controls underwent the identical subset of standardized examinations (BMI, % body fat, waist-to-hip ratio, skin fold thickness, native dietary composition examined by 7-day food records, etc.). No significant casecontrol differences in genotype distributions or allelic frequencies were observed. There were no differences in genotype frequencies between males and females either. The prevalence of obesity was significantly higher among subjects with the II genotype (42 %) when compared with those with DD (36%) and those with ID (37%) genotypes (P = 0.04). When compared with carbohydrate intake in the whole studied cohort, the odds ratios of carrying the DD allele in the morbidly obese cohort were 0.84 (95% CI 0.34, 2.10, P = 0.17), 0.27 (0.07, 0.98, P = 0.02), and 4.25 (1.44, 12.51, P = 0.005) in those individuals consuming \210, 210-260, and [260 g of carbohydrates/day, respectively. Based on our findings, the ID ACE polymorphism could represent a gene modulator of carbohydrate intake in morbidly obese Czech population; the strong significant effect of DD genotype was observed in the phenotypes of extreme obesity with the highest carbohydrate intake.

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A general model of intake regulation

Cited by 71 publications

References 114 publications

Sensory-specific satiety with simple foods in humans: no influence of BMI?

Sensory-specific satiety with simple foods in humans: no influence of BMI?

The Effects of Environmental Conditions on Activity, Feeding, and Body Weight in Male and Female Adolescent Rats

Effect of ID ACE gene polymorphism on dietary composition and obesity-related anthropometric parameters in the Czech adult population

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