A Generation of Laparoscopic Nephrectomy: Stage-Specific Surgical and Oncologic Outcomes for Laparoscopic Nephrectomy in a Single Center

Laird, A. Douglas; Stewart, Grant D.; Zhong, Jim; Ang, Wen-Jeat; Cutress, Mark L.; Riddick, Antony C. P.; McNeill, S. Alan; Tolley, David A.

doi:10.1089/end.2012.0562

Cited by 6 publications

(3 citation statements)

References 37 publications

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“…16,21 In this regard, laparoscopic surgery appears technically safe and feasible in this population.…”

Section: Discussionmentioning

confidence: 96%

“…Some studies have attempted to demonstrate the efficacy and safety of laparoscopic surgery in a similar population; 16,17,[21][22][23] however, single-centre analyses, minimal patient numbers or short follow-up periods limit their generalizability. Our multi-institutional design allows us to include many patients in a contemporary time period, not easily accomplished in single-centre studies.…”

Section: Discussionmentioning

confidence: 99%

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Clinical outcomes following laparoscopic management of pT3 renal masses: A large, multi-institutional cohort

Nayak

Patel

Bjazevic

et al. 2015

CUAJ

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Introduction: We described the clinical and oncological outcomes of patients treated by laparoscopic surgery for non-metastatic pT3 renal cell carcinoma (RCC). Methods: We queried a multi-institutional database for patients diagnosed with non-metastatic pathological T3 RCC from 13 Canadian centres treated laparoscopically (radical or partial nephrectomy) between 2008 and 2014. Clinical and pathological outcomes were evaluated. Progression was defined as the development of recurrence or metastatic disease. Log-rank testing and Kaplan-Meier statistical methods assessed for differences and estimated progression-free survival (PFS). Results: In total, 176 patients were identified with a median age of 64 years. The median tumour size was 7.0 cm. Pre-clinical stage was cT1 to cT4 in 39%, 28%, 30% and 3%, respectively. The median blood loss was 150 mL (range: 0-6000) and the median operative time was 124 minutes (range: 60-360). Most lesions were clear cell RCC (80%). After a median follow-up of 17.6 months (range: 0.2-75.0), disease progression occurred in 26% (46/176) of patients, consisting of local recurrence in 7% (3/46), and metastatic disease in 93% (43/46). The 3-year PFS was 67%, with a median PFS of 49 months. Of those who progressed, the median time to progression was 10.3 months. Conclusions: This study is the largest cohort of pT3 RCC patients treated laparoscopically in the literature and suggests that for properly selected patients, laparoscopic management of locally advanced renal masses yields acceptable short-term oncological outcomes.

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“…16,21 In this regard, laparoscopic surgery appears technically safe and feasible in this population.…”

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Clinical outcomes following laparoscopic management of pT3 renal masses: A large, multi-institutional cohort

Nayak

Patel

Bjazevic

et al. 2015

CUAJ

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“…La seguridad oncológica de la nefrectomía laparoscópica ya ha sido demostrada por diferentes autores. 29,30 El seguimiento a largo plazo de la nefrectomía laparoscópica confiere los mismos resultados que la cirugía abierta.…”

Section: Wwwmedigraphicorgmxunclassified

Nefrectomía laparoscópica: experiencia en el Centro Médico ABC, México

Madrid¹,

Gaytán²,

Vasquez-Lastra³

et al. 2021

Anales Médicos De La Asociación Médica Del Centro Médico ABC

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La nefrectomía laparoscópica es hoy en día el procedimiento de elección en casos seleccionados comparada con la cirugía abierta gracias a su baja morbilidad, mortalidad y rápida reintegración a las actividades normales del paciente. Objetivo: Presentar nuestra experiencia en nefrectomía laparoscópica tanto de patología oncológica como benigna, abordando características trans-y postoperatorias, así como criterios de selección para la población en cuestión. Material y métodos: De enero del 2006 a enero del 2020, un total de 110 pacientes fueron tratados con nefrectomía laparoscópica por nuestro grupo. Se documentó tiempo quirúrgico, sangrado, días de estancia intrahospitalaria, complicaciones, así como estirpe histológico definitivo. Resultados: El tiempo quirúrgico promedio fue de 131 minutos. De acuerdo con la indicación quirúrgica, 67 pacientes (61%) fueron sometidos a nefrectomía radical, 22 (20%) a nefroureterectomía y 21 pacientes (19%) a nefrectomía simple por exclusión renal. El tamaño tumoral promedio fue de 6.4 cm (rango 2.7 a 12 cm). El sangrado transoperatorio promedio fue de 103 mL (rango de 10-2,000 mL) y el promedio de días de estancia intrahospitalaria fue de 2.7 días. Sólo se presentó un caso de sangrado postoperatorio que se resolvió mediante laparoscopia. Conclusiones: La cirugía laparoscópica se ha establecido como el estándar de oro para el manejo de cáncer renal. Es también el procedimiento de elección en nefroureterectomía y en nefrectomía simple, así como en procedimientos reconstructivos de vías urinarias. Los resultados estéticos, con una rápida recuperación y ABSTRACT Introduction: Laparoscopic nephrectomy is currently considered as the preferred option over open surgery in select cases due to its low morbidity, risk and overall patient satisfaction. Objective: To present our experience in benign and oncologic laparoscopic nephrectomy, analyzing operative and postoperative characteristics of the population studied. Material and methods: From January 2006 to January 2020 a total of 110 patients were treated with laparoscopic nephrectomy. Surgical time, intraoperative bleeding, hospital stay and complications were documented. Results: Radical nephrectomy was performed in 67 (61%) patients, nephroureterectomy in 22 (20%) and simple nephrectomy in 21 (19%). Tumor size was 6.4 cm (range 2.7-12 cm). Bleeding was 103 mL (range 10-2,000 mL) and length of stay was 2.7 days. Only one case of reintervention was recorded due to postoperative bleeding that was resolved laparoscopically. Conclusions: Renal laparoscopic surgery is currently the gold standard for localized renal tumors, urothelial carcinomas, simple nephrectomies and reconstructive procedures. Cosmetic results along with a fast recovery and good oncologic control make it the procedure of choice for kidney surgery.

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Matched pair analysis of laparoscopic versus open radical nephrectomy for the treatment of T3 renal cell carcinoma

et al. 2014

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A Generation of Laparoscopic Nephrectomy: Stage-Specific Surgical and Oncologic Outcomes for Laparoscopic Nephrectomy in a Single Center

Cited by 6 publications

References 37 publications

Clinical outcomes following laparoscopic management of pT3 renal masses: A large, multi-institutional cohort

Clinical outcomes following laparoscopic management of pT3 renal masses: A large, multi-institutional cohort

Nefrectomía laparoscópica: experiencia en el Centro Médico ABC, México

Matched pair analysis of laparoscopic versus open radical nephrectomy for the treatment of T3 renal cell carcinoma

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