A glimpse of biodegradable polymers and their biomedical applications

Shah, Tejas V.; Vasava, Dilip V.

doi:10.1515/epoly-2019-0041

Cited by 94 publications

(43 citation statements)

References 241 publications

(242 reference statements)

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“…In recent years, many biologically derived materials have gained attention in the medical field (74). Inspired by the ability of natural spider silk to stop bleeding and promote wound healing, researchers hope to develop a new vascular graft.…”

Section: Medical Applicationsmentioning

confidence: 99%

Mechanical properties and application analysis of spider silk bionic material

Mou

et al. 2020

E-Polymers

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Spider silk is a kind of natural biomaterial with superior performance. Its mechanical properties and biocompatibility are incomparable with those of other natural and artificial materials. This article first summarizes the structure and the characteristics of natural spider silk. It shows the great research value of spider silk and spider silk bionic materials. Then, the development status of spider silk bionic materials is reviewed from the perspectives of material mechanical properties and application. The part of the material characteristics mainly describes the biocomposites based on spider silk proteins and spider silk fibers, nanomaterials and man-made fiber materials based on spider silk and spider-web structures. The principles and characteristics of new materials and their potential applications in the future are described. In addition, from the perspective of practical applications, the latest application of spider silk biomimetic materials in the fields of medicine, textiles, and sensors is reviewed, and the inspiration, feasibility, and performance of finished products are briefly introduced and analyzed. Finally, the research directions and future development trends of spider silk biomimetic materials are prospected.

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Section: Medical Applicationsmentioning

confidence: 99%

Mechanical properties and application analysis of spider silk bionic material

Mou

et al. 2020

E-Polymers

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“…Proof of that is the massive ongoing research for the use of these polymers in the biomedical field where the number of targets application is endless [300]. The same goes for synthetic biodegradable polymers [301]. In fact, the state-of-the-art fluoropolymers, e.g., poly(vinylidene difluoride) (PVdF), are not only expensive, but require a toxic solvent (i.e., N-methyl-2-pyrrolidone, NMP) for electrode manufacturing.…”

Section: Biobased Gpesmentioning

confidence: 99%

A Review of the Use of GPEs in Zinc-Based Batteries. A Step Closer to Wearable Electronic Gadgets and Smart Textiles

2020

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With the flourish of flexible and wearable electronics gadgets, the need for flexible power sources has become essential. The growth of this increasingly diverse range of devices boosted the necessity to develop materials for such flexible power sources such as secondary batteries, fuel cells, supercapacitors, sensors, dye-sensitized solar cells, etc. In that context, comprehensives studies on flexible conversion and energy storage devices have been released for other technologies such Li-ion standing out the importance of the research done lately in GPEs (gel polymer electrolytes) for energy conversion and storage. However, flexible zinc batteries have not received the attention they deserve within the flexible batteries field, which are destined to be one of the high rank players in the wearable devices future market. This review presents an extensive overview of the most notable or prominent gel polymeric materials, including biobased polymers, and zinc chemistries as well as its practical or functional implementation in flexible wearable devices. The ultimate aim is to highlight zinc-based batteries as power sources to fill a segment of the world flexible batteries future market.

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“…Moreover, when used for the creation of bioengineered scaffolds for wound healing, these polymers must provide a 3D architecture according to the structural heterogeneity of the host tissue environment [84,85]. The previous allows improving the mechanical and cellular activity (e.g., adhesion and proliferation) required by these structures [86][87][88]. In addition, scaffold design needs to consider several features such as cell-tissue interaction, vascularization, scaffold degradation, and loading with drugs, growth factors, cells, and antibacterial material.…”

Section: Bioengineered Thermo-responsive Scaffoldsmentioning

confidence: 99%

Bioengineered Scaffolds for Thermo-responsive Drug Delivery in Wound Healing

Henríquez¹,

Castro-Alpízar²,

Lopretti-Correa³

et al. 2020

Preprint

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innate and adaptive immune responses lead to wound healing by regulating a complex series of events promoting cellular cross-talk. An inflammatory response is presented with its characteristic clinical symptoms: heat, pain, redness, and swelling. Some smart thermo-responsive polymers like chitosan can be used to create biocompatible and biodegradable scaffolds with 3D architectures similar to human structures, allowing their efficient and safe use as tissue engineering and drug delivery systems in chronic wounds. Locally heated tumors above polymer lower critical solution temperature can induce its conversion into a hydrophobic form, enhancing drug release until the thermal stimulus is gone, where a lower release is due to the swelling of the material. This paper integrates the relevant reported contributions of bioengineered scaffolds for thermo-responsive drug delivery in wound healing. Therefore, we present a comprehensive review that aims to demonstrate the capacity of these systems to provide spatially and temporally controlled release strategies for one or more drugs used in wound healing. In this sense, the novel manufacturing techniques of 3D-printing and electrospinning are explored for the tuning of their physicochemical properties to adjust therapies according to the patient’s convenience, as well as reduce drug toxicity and side effects.

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A glimpse of biodegradable polymers and their biomedical applications

Cited by 94 publications

References 241 publications

Mechanical properties and application analysis of spider silk bionic material

Mechanical properties and application analysis of spider silk bionic material

A Review of the Use of GPEs in Zinc-Based Batteries. A Step Closer to Wearable Electronic Gadgets and Smart Textiles

Bioengineered Scaffolds for Thermo-responsive Drug Delivery in Wound Healing

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