“…Sixteen input parameters were included in the optimization: ALC and PFL initial strain and stiffness, localized LCL and sMCL strain (anterior, middle, posterior bundles), LCL and sMCL stiffness (applied to all bundles), and inferior-superior and anterior-posterior LCL and sMCL femoral attachment locations. Strain for each ligament during the optimization was bounded at 74% Arms et al, 1983); stiffness for each ligament was varied within values reported in the literature (Arms et al, 1983;Griffith et al, 2009;Mommersteeg et al, 1996;LaPrade et al, 2004). Although the specimen-specific LCL and MCL tibial and femoral attachment sites were identified through dissection, the fibers carrying load throughout the passive femoral flexion range were unknown and could exist anywhere within the attachment footprint.…”