A glucose biosensor based on microporous polyacrylonitrile synthesized by single rare-earth catalyst

Zheng, Hao; Han, Xue; Zhang, Yifeng; Shen, Zhiquan

doi:10.1016/s0956-5663(02)00010-6

Cited by 106 publications

(54 citation statements)

References 14 publications

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“…Since the surface area of the electrode, the quantity of the enzyme, and the concentration of substrate are constant, the steady state current is proportional to the rate constant K [24][25][26]. We replaced ln K with ln Di in the Arrhenius formula.…”

Section: Influential Factors On the Response Characteristics Of The Pmentioning

confidence: 99%

An amperometric glucose biosensor based on poly(o-aminophenol) and Prussian blue films at platinum electrode

Pan

Chen

Nie

et al. 2004

Analytical Biochemistry

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Section: Influential Factors On the Response Characteristics Of The Pmentioning

confidence: 99%

An amperometric glucose biosensor based on poly(o-aminophenol) and Prussian blue films at platinum electrode

Pan

Chen

Nie

et al. 2004

Analytical Biochemistry

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“…There have been several methods for constructing GOx/CNT biosensors including adsorption [18], crosslinking [19], electrochemical copolymerization [20], covalent attachment, and entrapment in polymeric gels or carbon paste [21]. Among various enzymes immobilization, electrostatic layer-by-layer adsorption was simplest and most powerful methods for creating ordered, stable and biocompatible multilayer films.…”

Section: Introductionmentioning

confidence: 99%

Biosensor Based on Self‐Assembling Glucose Oxidase and Dendrimer‐Encapsulated Pt Nanoparticles on Carbon Nanotubes for Glucose Detection

Zhu

Tang

et al. 2007

Electroanalysis

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A novel amperometric glucose biosensor based on layer-by-layer (LbL) electrostatic adsorption of glucose oxidase (GOx) and dendrimer-encapsulated Pt nanoparticles (Pt-DENs) on multiwalled carbon nanotubes (CNTs) was described. Anionic GOx was immobilized on the negatively charged CNTs surface by alternatively assembling a cationic Pt-DENs layer and an anionic GOx layer. Transmission electron microscopy images and z-potentials proved the formation of layer-by-layer nanostructures on carboxyl-functionalized CNTs. LbL technique provided a favorable microenvironment to keep the bioactivity of GOx and prevent enzyme molecule leakage. The excellent electrocatalytic activity of CNTs and Pt-DENs toward H 2 O 2 and special three-dimensional structure of the enzyme electrode resulted in good characteristics such as a low detection limit of 2.5 mM, a wide linear range of 5 mM -0.65 mM, a short response time (within 5 s), and high sensitivity (30.64 mA mM À1 cm À2) and stability (80% remains after 30 days).

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“…Figure 4B shows the cyclic voltammograms obtained from AuNP/GOX-containing electrodes in the absence of VF. In this case electron transfer is likely mediated by AuNPs but may also be occurring by direct contact between the prosthetic group (FAD/FADH 2 ) of GOX and the electrode surface [32]. The anodic current once again increased as varying concentrations of glucose were introduced into the system.…”

Section: Detection Of Glucose and Hydrogen Peroxide Using Nanocomposimentioning

confidence: 99%

Micropatterned Nanocomposite Hydrogels for Biosensing Applications

et al. 2011

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This paper describes the use of Au nanoparticle (NP)-containing hydrogel microstructures in the development of electrochemical enzyme-based biosensors. To fabricate biosensors, AuNPs were conjugated with glucose oxidase (GOX) or horseradish peroxidase (HRP) molecules and were dispersed in the prepolymer solution of poly(ethylene glycol) diacrylate (PEG-DA). Vinylferrocene (VF) was also added into the prepolymer solution in order to lower operating potential of the biosensor and to prevent oxidation of interfering substances. The prepolymer solution was photolithographically patterned in alignment with an array of Au electrodes fabricated on glass. As a result, electrode arrays became functionalized with AuNP/GOX-or AuNP/HRP-carrying hydrogel microstructures. Performance of the biosensors was characterized by impedance spectroscopy, chronoapmerometry and cyclic voltammetry. Impedance measurements revealed that inclusion of Au nanoparticles improved conductivity of PEG hydrogel by a factor of 5. Importantly, biosensors based on AuNP-GOX complex exhibited high sensitivity to glucose (100 mA mM À1 cm À2) in the linear range from 0.1 to 10 mM. The detection limit was estimated to be 3.7 10-7 M at a signal-to-noise ratio of 3. Biosensors with immobilized AuNP/HPR had a linear response from 0.5 to 5.0 mM of hydrogen peroxide with sensitivity of 1.4 mA mM À1 cm À2. The method for fabricating nanoparticle-carrying hydrogel microstructures described in this paper should be widely applicable in the development of robust and sensitive electrochemical biosensors.

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A glucose biosensor based on microporous polyacrylonitrile synthesized by single rare-earth catalyst

Cited by 106 publications

References 14 publications

An amperometric glucose biosensor based on poly(o-aminophenol) and Prussian blue films at platinum electrode

An amperometric glucose biosensor based on poly(o-aminophenol) and Prussian blue films at platinum electrode

Biosensor Based on Self‐Assembling Glucose Oxidase and Dendrimer‐Encapsulated Pt Nanoparticles on Carbon Nanotubes for Glucose Detection

Micropatterned Nanocomposite Hydrogels for Biosensing Applications

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