A hepatic lipoma mimicking angiomyolipoma of the liver: Report of a case

Nakamura, Noriaki; Kudo, Atsushi; Itō, Kōji; Tanaka, Shinji; Arii, Shigeki

doi:10.1007/s00595-008-3921-5

Cited by 13 publications

(6 citation statements)

References 17 publications

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“…Despite widespread of sensitive imaging studies and increasing report of benign hepatic tumours primary lipoma of the liver is seldom encountered. 3 …”

Section: Discussionmentioning

confidence: 99%

Liver lipoma: a case report

et al. 2017

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Liver lipoma is a rare benign mesenchymal tumour without malignant degeneration. Lesions may be asymptomatic, nevertheless they may sometimes cause abdominal pain depending upon the size. Usually liver lipomas are an incidental finding during radiological examinations performed for other reasons, and there is no evidence of familiar genetic cluster or predisposing factors but it seems to have a strong association with impaired lipidic profile. In this report, we describe the case of a 72 year old female with a giant liver lipoma observed during an ultrasound examination. The clinical examination was completed with CT and MRI scans. Features of the lesion such as negative attenuation values on multiphasic CT examination and MRI signal drop-out on T2 spectral presaturation with inversion recovery sequences, with no enhancement after administration of contrast medium, are suggestive for this kind of benign neoplasm. The purpose of this report is provide an anthological case of liver lipoma, helping to define the diagnostic features with imaging techniques.

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“…Despite widespread of sensitive imaging studies and increasing report of benign hepatic tumours primary lipoma of the liver is seldom encountered. 3 …”

Section: Discussionmentioning

confidence: 99%

Liver lipoma: a case report

et al. 2017

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“…Primary or metastatic lipomatous tumor of the liver is extremely rare and may occasionally show an inflammatory background [17], but thick-walled blood vessels and the perivascular arrangement of epithelioid cells are seldom seen in these tumors. In addition, melanin marker (HMB-45) and muscle marker (SMA) will be helpful to diagnosis [17].…”

Section: Discussionmentioning

confidence: 99%

“…In addition, melanin marker (HMB-45) and muscle marker (SMA) will be helpful to diagnosis [17]. Sarcomatoid carcinoma always demonstrates obvious cytological atypia and does not have the thick-walled vessels and adipose tissue.…”

Section: Discussionmentioning

confidence: 99%

Inflammatory angiomyolipoma of the liver: a rare hepatic tumor

et al. 2012

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Angiomyolipoma (AML) is a rare mesenchymal neoplasm of the tumor, composed of a varying heterogeneous mixture of three tissue components: blood vessels, smooth muscle and adipose cells. Hepatic AML may demonstrate a marked histological diversity. We herein present one case of hepatic AML exhibiting prominent inflammatory cells in the background, which happened in a 61-year-old Chinese female patient, without signs of tuberous sclerosis. Histologically, the striking feature was the infiltration of numerous inflammatory cells in the background, including small lymphocytes, plasma cells, and eosnophils. The tumor cells were spindled and histiocytoid in shape, with slightly eosinophilic cytoplasm, and arranged along the vessels or scattered among the inflammatory background. Sinusoid structure was obviously seen in the tumor. Mature adipocytes and thick-walled blood vessels were focally observed at the boundaries between the tumor and surrounding liver tissues. The tumor cells were positive immunostaining for HMB-45, Melan-A, and smooth muscle actin. The inflammatory AML should be distinguished from other tumors with inflammatory background such as inflammatory myofibroblastic tumor and follicular dendritic cell tumor and deserves wider recognition for its occurrence as a primary hepatic tumor.Virtual slidesThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1828633072762370

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“…Fat is of low attenuation (hypodense) compared with normal liver parenchyma at computed tomography (CT), with a range of -10 to -100 HU, and high in signal intensity (hyperintence) on T1-weighted magnetic resonance (MR) images [5]. In addition, several MR imaging sequences aid in the detection of fat, including fat suppression sequences (hypointence) and chemical shift imaging with opposed-phase gradient-echo sequences [6,7].…”

Section: Discussionmentioning

confidence: 99%

“…Although some hepatic lipomas may mimick angiomiolipomas [8,9], they don't carry malignant potential and there are many characteristic findings on US, CT and MRI, which are satisfactory evidences for hepatic lipoma diagnosis. Therefore many authors do not recommend more aggressive diagnostic procedures, such as needle liver biopsy and operation [10].…”

Section: Discussionmentioning

confidence: 99%

Hepatic Lipoma: Radiological Imaging Findings

Koplay¹,

Hacioğlu²,

Algın³

2011

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Hemangiomas and hepatic metastases are the leading reasons of echogenic masses on ultrasound (US) evaluation of the liver. Lipomas of the liver are extremely rare and have been sporadically reported in the literature during the last century. The present report describes a patient with hepatic lipoma together with liver metastases from gastric adenocarcinoma. A 54 years old woman was refered to our department because of abdominal pain. Patient has been operated for gastric adenocarcinoma 3 months ago she was evaluated with US, computed tomography (CT) and magnetic resonance imaging (MRI).The abdominal US revealed a 12 × 10 mm echogenic mass with smooth borders in 7th segment of the liver. CT scan showed a hypodense lesion in the same hepatic segment with fat dencity and no contrast involvement. MRI demonstrated the same lesion on T1 and T2 weighted images as hyperintence mass. The final radiographic diagnosis was he-patic lipoma. However, there was metastas in the liver of patient. Patient died 4 months later due to metas-tatic gastric adenocarcinoma. Hepatic lipoma should be kept in mind in echogenic masses on US evaluation of the liver

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A hepatic lipoma mimicking angiomyolipoma of the liver: Report of a case

Cited by 13 publications

References 17 publications

Liver lipoma: a case report

Liver lipoma: a case report

Inflammatory angiomyolipoma of the liver: a rare hepatic tumor

Hepatic Lipoma: Radiological Imaging Findings

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