A high throughput screen to test the biocompatibility of water-miscible ionic liquids

Ionic Liquid Gel‐Assisted Electrodes for Long‐Term Cutaneous Recordings

“…ILs have been used in many biological applications, including as solvents that enhance the stability of proteins. [ 17 ] Although several IL families showing low cytotoxicity have been identifi ed, [18][19][20] the establishment of general design rules for IL biocompatibility is the focus of ongoing work. ILs can be polymerized to yield gels, which are especially appealing for use as a quasi-solid-state electrolytes.…”

Antimicrobial Ionic Liquids

“…Recently, this method has been championed by Stephens and co-workers (Rebros et al, 2009;Wood & Stephens, 2010) as a simple method for rapid determination of relative toxicity of ionic liquids. This simple, inexpensive method has been suggested as a basic requirement in the toxicological assessment of ionic liquids and, since it requires neither specialist equipment nor advanced microbiological techniques, may be performed routinely in laboratories conducting research into ionic liquids with minimum microbiological expertise.…”

Alkyl-methylimidazolium ionic liquids affect the growth and fermentative metabolism of Clostridium sp.

“…Several studies have documented that ILs are persistent in the environment and exhibit toxicity towards microbes and cells (Carson et al, 2009;Kulacki and Lamberti, 2007;Latala et al, 2009;Ranke et al, 2007;Rebros et al, 2009;Romero et al, 2008;Wang et al, 2010;Zhang et al, 2010). Toxicity of the IL depends on cation, anion and substituents of cation.…”