A highly selective and sensitive chemosensor for instant detection cyanide via different channels in aqueous solution

Zhang, Peng; Shi, Bingbing; You, Xing-Mei; Zhang, Youming; Lin, Qian; Yao, Hong; Wei, Tai‐Bao

doi:10.1016/j.tet.2014.01.046

Cited by 61 publications

(16 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…40). 64 As there was two imine groups the probe followed 1:2 binding stoichiometry, confirmed by Jobs plot. The detection level was found to be 4.0 × 10 -7 M.…”

Section: Page 18 Of 37mentioning

confidence: 78%

Organic chemodosimeter for cyanide: A nucleophilic approach

Pati

2016

Sensors and Actuators B: Chemical

View full text Add to dashboard Cite

“…40). 64 As there was two imine groups the probe followed 1:2 binding stoichiometry, confirmed by Jobs plot. The detection level was found to be 4.0 × 10 -7 M.…”

Section: Page 18 Of 37mentioning

confidence: 78%

Organic chemodosimeter for cyanide: A nucleophilic approach

Pati

2016

Sensors and Actuators B: Chemical

View full text Add to dashboard Cite

“…As a general rule, these systems rely on the unique nucleophilic reactivity of the cyanide anion to trigger a change in the fluorescent response. 12 Fluorescent probes for the cyanide anion that are based on its interactions with metal ions, 13 H + , 14 and boronic acid derivatives 15 are also known. To date, cyanide anion probes have been used to sense endogenous cyanide in plant samples.…”

Section: Introductionmentioning

confidence: 99%

A Mitochondria-Specific Fluorescent Probe for Visualizing Endogenous Hydrogen Cyanide Fluctuations in Neurons

Long

Huang²,

Wang³

et al. 2018

J. Am. Chem. Soc.

163

View full text Add to dashboard Cite

An ability to visualize HCN in mitochondria in real time may permit additional insights into the critical toxicological and physiological roles this classic toxin plays in living organisms. Herein, we report a mitochondria-specific coumarin pyrrolidinium-derived fluorescence probe (MRP1) that permits the real-time ratiometric imaging of HCN in living cells. The response is specific, sensitive (detection limit is ca. 65.6 nM), rapid (within 1 s), and reversible. Probe MRP1 contains a benzyl chloride subunit designed to enhance retention within the mitochondria under conditions where the mitochondria membrane potential is eliminated. It has proved effective in visualizing different concentrations of exogenous HCN in the mitochondria of HepG2 cells, as well as the imaging of endogenous HCN in the mitochondria of PC12 cells and within neurons. Fluctuations in HCN levels arising from the intracellular generation of HCN could be readily detected.

show abstract

“…Therefore, the determination of cyanide ions in aqueous environment is a very interesting subject. 2 In addition, cyanide anions strongly coordinate with transition metals due to their high nucleophilic character. Thanks to these properties, cyanide anions may bind to Fe(III) ions in the active center of enzymes and proteins such as cytochrome-c and hemoglobin when the amount of cyanide in the living organism rises above safe limits.…”

Section: Introductionmentioning

confidence: 99%

A simple azoquinoline based highly selective colorimetric sensor for CN⁻ anion in aqueous media

Koç

Özay

2017

Can. J. Chem.

View full text Add to dashboard Cite

Azoquinoline based sensor AZQ was designed and synthesized as a new molecular ion sensor containing an azo group in its structure. The structural characterization of AZQ was carried out using FTIR, NMR, mass, and elemental analysis. Then, the interaction of AZQ with anions was observed visually and UV–vis measurements were made in EtOH/H2O (1:1, v/v) solvent mixture. As a result of this investigation, it was determined that AZQ is a fast and highly selective sensor for CN− ions. The solution colour of AZQ changed from light yellow to orange only in the presence of CN− ions. The limit of detection of AZQ was calculated as 2.6 μmol/L from anion titration experiments. Also, to identify the interaction mechanism of AZQ with CN− ions, 1H NMR spectra of AZQ in the presence of CN− anions were recorded and the structure was proposed for AZQ-CN− host–guest complex.

show abstract

A highly selective and sensitive chemosensor for instant detection cyanide via different channels in aqueous solution

Cited by 61 publications

References 37 publications

Organic chemodosimeter for cyanide: A nucleophilic approach

Organic chemodosimeter for cyanide: A nucleophilic approach

A Mitochondria-Specific Fluorescent Probe for Visualizing Endogenous Hydrogen Cyanide Fluctuations in Neurons

A simple azoquinoline based highly selective colorimetric sensor for CN⁻ anion in aqueous media

Contact Info

Product

Resources

About

A highly selective and sensitive chemosensor for instant detection cyanide via different channels in aqueous solution

Cited by 61 publications

References 37 publications

Organic chemodosimeter for cyanide: A nucleophilic approach

Organic chemodosimeter for cyanide: A nucleophilic approach

A Mitochondria-Specific Fluorescent Probe for Visualizing Endogenous Hydrogen Cyanide Fluctuations in Neurons

A simple azoquinoline based highly selective colorimetric sensor for CN− anion in aqueous media

Contact Info

Product

Resources

About

A simple azoquinoline based highly selective colorimetric sensor for CN⁻ anion in aqueous media