A Highly Vascular Intracranial Solitary Fibrous Tumor Treated with Radiotherapy and Toremifene: Case Report

Macfarlane, Rebecca; Galloway, Malcolm; Plowman, P N; Thomas, David G. T.

doi:10.1227/01.neu.0000159717.37748.b5

Cited by 28 publications

(19 citation statements)

References 25 publications

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“…b Immunostaining for CD34. The tumor cells were strongly positive for CD34, which is invariably expressed by solitary fibrous tumors (immunohistochemistry, 9200) literature [10]. Because the present tumor was located very close to the anal canal, we performed transanal needle biopsy, and made a definite diagnosis of SFT.…”

Section: Discussionmentioning

confidence: 81%

Giant intrapelvic solitary fibrous tumor arising from mesorectum

Soda

Kainuma

Yamamoto

et al. 2010

Clin J Gastroenterol

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We report a patient who had a giant pelvic solitary fibrous tumor (SFT) that was excised with the aid of aortic balloon occlusion. A 27-year-old woman was diagnosed, at another hospital, as having an inoperable intrapelvic tumor. On admission, computed tomography showed that the uterus, urinary bladder, and rectum were compressed anteriorly by a pelvic tumor with a maximum diameter of 16 cm. On magnetic resonance imaging, the tumor contained mesh-like structures showing strong intensity. Transanal needle biopsy was performed, and SFT was diagnosed by immunostaining. The tumor was supplied by feeding vessels from the inferior mesenteric artery and bilateral internal iliac arteries. Despite massive intraoperative hemorrhage, this giant tumor was excised with the help of aortic balloon occlusion. An intrapelvic SFT should be resected after careful preparation of countermeasures for hemorrhage.

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Section: Discussionmentioning

confidence: 81%

Giant intrapelvic solitary fibrous tumor arising from mesorectum

Soda

Kainuma

Yamamoto

et al. 2010

Clin J Gastroenterol

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“…Only eleven cases have been repoted to date (5). Clinical manifestations of the tumors depends on the anatomical site involved and include exophthalmos (1), loss of vision (10), hemiparesis (1), hearing loss (17), facial palsy (17), headache (8,10), seizures and papilloedema (18). Imaging characteristics resemble those of meningiomas.…”

Section: Discussionmentioning

confidence: 99%

“…Radiotherapy is administered if the excision is subtotal or partial (8,10,12,23). The chemotherapeutic agent Toremifene can also be administered if the proliferation rate is high (10).…”

Section: Discussionmentioning

confidence: 99%

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Solitary fibrous tumor of the tentorium – a case report

Alapatt

Ajaya²,

Govindan³

et al. 2010

Turkish Neurosurgery

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The authors describe the clinical and pathological features of a solitary fibrous tumor of the tentorium, a rare location for the tumor in the CNS. A 52-year-old lady presented to the neurosurgical services with headache of four months and vertigo of one and a half months duration. On examination, she had left-sided cerebellar signs and bilateral papilloedema. Cranial MR imaging showed an enhancing tumor based on the left tentorium. Clinical impression was a meningioma. The patient underwent left suboccipital craniectomy. The tumor was firm and vascular, extending above the tent through a defect. Total excision was achieved. The correct diagnosis of solitary fibrous tumor could be made only by histopathology. Solitary fibrous tumors of the tentorium, though rare, should be included in the differential diagnosis of dural based masses.KeywoRds: Solitary fibrous tumor, Tentorium, Meningioma, CD 34, Hemangiopericytoma, Vimentin ÖZ Yazarlar MSS'de tümör için nadir bir konum olan tentoriuumda soliter fibröz tümörün klinik ve patolojik özelliklerini tanımlamaktadır. 52 yaşında bir kadın hasta beyin cerrahisi polikliniğine dört aydır başağrısı ve bir buçuk aydır başdönmesiyle başvurdu. Muayenede sol tarafta serebellar bulgular ve bilateral papilla ödemi mevcuttu. Kraniyal MR görüntüleme sol tentorium temelli kontrast tutan bir tümör gösterdi. Klinik izlenim menenjiyomdu. Hastaya suboksipital kraniyektomi yapıldı. Tümör sert ve vaskülerdi ve bir defekt yoluyla çadırın üzerine uzanmaktaydı. Total eksizyon yapıldı. Soliter fibröz tümörün doğru tanısı sadece histopatoloji ile konabildi. Tentorium soliter fibröz tümörleri nadir olmalarına rağmen dura kökenli kitlelerin ayırıcı tanısında dikkate alınmalıdır.ANAHTAR sÖZCÜKLeR: Soliter fibröz tümör, Tentorium, Menenjiyom, CD 34, Hemanjiyoperisitom, Vimentin

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“…8,9) SFT is believed to be extremely rare in the central nervous system (CNS). SFT in the CNS shows similar histological characteristics to fibrous meningioma and hemangiopericytoma (HPC).…”

Section: Introductionmentioning

confidence: 99%

Recurrent Solitary Fibrous Tumor of the Falx Cerebri With Intraventricular Extension-Case Report-

Teranishi

Yamamoto

Nakao

et al. 2007

Neurol. Med. Chir.(Tokyo)

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A 61-year-old male presented with a recurrent solitary fibrous tumor (SFT) arising from the falx cerebri with intraventricular extension manifesting as nausea and vomiting. Magnetic resonance imaging showed the heterogeneously enhanced tumor in the falx, which extended to the bilateral lateral ventricles and the third ventricle. Total tumor removal was performed via the bifrontal interhemispheric approach. Histological examination showed mostly spindle cells with rich intercellular fibers. Immunohistochemical examination showed strong staining for CD34 in the cytoplasm but no staining for epithelial membrane antigen. Reexamination of the two previous tumor specimens, previously identified as fibrous meningioma, found SFT. The differential diagnosis of SFT in the central nervous system from fibrous meningioma and hemangiopericytoma requires immunohistochemistry and electron microscopy.

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A Highly Vascular Intracranial Solitary Fibrous Tumor Treated with Radiotherapy and Toremifene: Case Report

Abstract: The use of surgery, radiotherapy, and toremifene in treatment of a vascular intracranial solitary fibrous tumor has been successful and warrants further research.

Cited by 28 publications

References 25 publications

Giant intrapelvic solitary fibrous tumor arising from mesorectum

Giant intrapelvic solitary fibrous tumor arising from mesorectum

Solitary fibrous tumor of the tentorium – a case report

Recurrent Solitary Fibrous Tumor of the Falx Cerebri With Intraventricular Extension-Case Report-

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