“…Nygaard Ostby introduced ethylenediaminetetraacetic acid for canal irrigation in 1957, 6 and finally in 1963 endodontics was recognized as a separate dental specialty by the American Dental Association. 7 In 1993, a revolutionary material for the apical sealing in retrograde filling material, furcation repair, was introduced by Parirokh and Torabinejad. 12 It is an ideal retrograde filling material for root end sealing with nontoxic, noncarcinogenic, nongenotoxic, biocompatible, insoluble properties in tissue fluids, and dimensionally stable.…”