This paper focuses on a simulation platform to model and simulate the energy consumption of a building with multiple zones under the influence of daily and seasonal environmental factors, as well as the impact of the HVAC system and human activities. By using model-based requirements engineering (MBRE), the requirements of the simulation platform are hierarchically derived and specified. On this basis, the simulation platform is designed and developed. With the help of the simulation platform, it is possible to obtain a mathematical model for a realistic description of the thermodynamics and energy consumption of the individual zones of a building, which can be used as a basis for the model-based development of the energy management system, e.g. intelligent energy dispatch strategy. In the following, the concept of the simulation platform and the process will be demonstrated and validated with an application example of the research building Open Mobility Lab (OML).