A hydrogel sheet mask with tea tree essential oil entrapment and targeted dose delivery capability

Ghosh, Biva; Bhattacharya, Debalina; Mukhopadhyay, Mainak

doi:10.1016/j.matpr.2022.01.349

Cited by 5 publications

(4 citation statements)

References 33 publications

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“…Using these two essential oils in gellan gum hydrogels at 25% w/w resulted in an efficient zone of inhibition of 20 mm against S. aureus and 30 mm against E. coli in standard disc diffusion assays [73]. Several studies have used different essential oils in hydrogels, such as basil oil [74], tea tree oil [75], sweet fennel oil [76], rosemary essential oil, orange essential oil [77], and Thymus daenesis oil [78], to improve their antibacterial activity. In addition to essential oils, plant extracts have been used as additives in hydrogel wound dressings.…”

Section: Hydrogelsmentioning

confidence: 99%

Recent Advances in Using Natural Antibacterial Additives in Bioactive Wound Dressings

et al. 2023

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Wound care is a global health issue with a financial burden of up to US $96.8 billion annually in the USA alone. Chronic non-healing wounds which show delayed and incomplete healing are especially problematic. Although there are more than 3000 dressing types in the wound management market, new developments in more efficient wound dressings will require innovative approaches such as embedding antibacterial additives into wound-dressing materials. The lack of novel antibacterial agents and the misuse of current antibiotics have caused an increase in antimicrobial resistance (AMR) which is estimated to cause 10 million deaths by 2050 worldwide. These ongoing challenges clearly indicate an urgent need for developing new antibacterial additives in wound dressings targeting microbial pathogens. Natural products and their derivatives have long been a significant source of pharmaceuticals against AMR. Scrutinising the data of newly approved drugs has identified plants as one of the biggest and most important sources in the development of novel antibacterial drugs. Some of the plant-based antibacterial additives, such as essential oils and plant extracts, have been previously used in wound dressings; however, there is another source of plant-derived antibacterial additives, i.e., those produced by symbiotic endophytic fungi, that show great potential in wound dressing applications. Endophytes represent a novel, natural, and sustainable source of bioactive compounds for therapeutic applications, including as efficient antibacterial additives for chronic wound dressings. This review examines and appraises recent developments in bioactive wound dressings that incorporate natural products as antibacterial agents as well as advances in endophyte research that show great potential in treating chronic wounds.

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Section: Hydrogelsmentioning

confidence: 99%

Recent Advances in Using Natural Antibacterial Additives in Bioactive Wound Dressings

et al. 2023

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“…Ghosh et al [ 86 ] fabricated a hydrogel scaffold with β-cyclodextrin and chitosan along with pectin, carboxymethyl cellulose, and polyethylene glycol 400 (PEG 400) as a plasticizer, and copper sulfate as crosslinker loaded with TTO, to enhance the antimicrobial activity in the treatment of acne and other skin infections. These scaffolds could be used as sheet masks or patches.…”

Section: Biological Properties Of Ttomentioning

confidence: 99%

“…was the microorganism used in the assay. Only the first formulation with TTO presented better physical characteristics along with the best antibacterial activity [ 86 ]. It could also deliver TTO in a more efficient way enhancing, therefore, the antibacterial activity.…”

Section: Biological Properties Of Ttomentioning

confidence: 99%

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Tea Tree Oil: Properties and the Therapeutic Approach to Acne—A Review

et al. 2023

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Acne vulgaris is an inflammatory dermatological pathology that affects mostly young people. However, it can also appear in adulthood, mainly in women. It has a high psychosocial impact, not only at the time of active lesions but also due to the consequences of lesions such as scarring and hyperpigmentation. Several factors are involved in the physiopathology of acne and the constant search for active ingredients is a reality, namely phytotherapeutic ingredients. Tea tree oil is an essential oil extracted from Melaleuca alternifolia (Maiden & Betch) Cheel with known antibacterial, anti-inflammatory, and antioxidant properties, making it a candidate for the treatment of acne. This review aims to describe the various properties of tea tree oil that make it a possible ingredient to use in the treatment of acne and to present several human studies that have evaluated the efficacy and safety of using tea tree oil in the treatment of acne. It can be concluded that tea tree oil has good antibacterial, anti-inflammatory, and antioxidant properties that result in a decrease in the number of inflammatory lesions, mainly papules, and pustules. However, given the diversity of study designs, it is not possible to draw concrete conclusions on the efficacy and safety of this oil in the treatment of acne.

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Effect of tea tree oil addition on the microstructure, structure and selected properties of chitosan-based coatings electrophoretically deposited on zirconium alloy substrates

Mielczarek

Marchewka²,

Kowalski³

et al. 2023

Applied Surface Science

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A hydrogel sheet mask with tea tree essential oil entrapment and targeted dose delivery capability

Cited by 5 publications

References 33 publications

Recent Advances in Using Natural Antibacterial Additives in Bioactive Wound Dressings

Recent Advances in Using Natural Antibacterial Additives in Bioactive Wound Dressings

Tea Tree Oil: Properties and the Therapeutic Approach to Acne—A Review

Effect of tea tree oil addition on the microstructure, structure and selected properties of chitosan-based coatings electrophoretically deposited on zirconium alloy substrates

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