A incidência regional do tromboembolismo venoso no Brasil

Abstract

Background: Several studies conducted in areas with temperate climates have suggested that the incidence of venous thromboembolism (VTE) varies depending on seasonal climatic fluctuations. However, no studies have been conducted comparing areas with semi-arid climate with areas with temperate climates. Objectives: To analyze whether there is a correlation between the incidence of VTE in areas with semi-arid climates and areas with temperate climates in Brazil. Methods: Retrospective data were acquired for patients diagnosed with VTE from January 2011 to December 2014 from the Brazilian National Health Service for the following Brazilian states that have semi-arid climates: Alagoas, Ceará, Maranhão, Paraíba, Pernambuco, Piauí, and Rio Grande do Norte (all located in the Northeast Region of Brazil); and the following states with temperate climates: Paraná, Santa Catarina, and Rio Grande do Sul (all located in the South Region of Brazil). Data on climatic variation were obtained from the National Meteorological Institute and population data were obtained from the Brazilian Institute of Geography and Statistics. Results: There was a significant correlation in the incidence of VTE cases in areas with lower temperatures (p < 0.001). The South Region exhibited significantly lower temperatures than the Northeast Region (p < 0.001) and had a significantly higher number of cases of VTE than the Northeast Region (p < 0.001). Conclusions: There are more cases of VTE in areas with temperate climates, where temperatures are lower. However, there is still little information in the literature on seasonal fluctuations and incidence of VTE. More studies of this subject are needed.

Diretriz Conjunta sobre Tromboembolismo Venoso – 2022

“…2 Na literatura, diversos estudos relacionam a presença de TEV com a variação climática. No Brasil, Ohki et al 4 relataram maior incidência de TEV nos estados do Sul, onde as temperaturas são mais baixas. A incidência de casos de TEV nesses locais apresentou uma média de 2,86 para cada 100.000 habitantes.…”

“…A incidência de casos de TEV nesses locais apresentou uma média de 2,86 para cada 100.000 habitantes. 4 Tal síndrome clínica aumenta exponencialmente com a idade, mesmo com a aplicação de estratégias de prevenção. 5 A mulheres são mais comumente afetadas na juventude, sobretudo no puerpério.…”

Análise de correlação em estudos clínicos e experimentais

“…It can be stated that there is a negative linear correlation between V1 and V3, just as Ohki and Bellen identified a moderate negative correlation (ρ = -0.65; p < 0.01) between average regional temperature and the incidence of venous thrombosis. 6 It can also be observed that the values for the correlation between V1 and V3 are closer to the imaginary straight line than the values for the correlation between V1 and V2. This invites the conclusion that the relationship between the values of the variables V1 and V3 is stronger than the relationship between V1 and V2, even though the directions are opposite.…”

Seasonal dynamics of myocardial infarctions in regions with different types of a climate: a meta-analysis

“…Although elevated sweating during heat contributes to hemoconcentration, this may be offset by increased water intake. Besides, in the Brazilian study, an association of an increase in thromboembolism incidents with a decrease in air temperature was revealed [ 66 ]. Moreover, the meta-analysis [ 4 ] showed that hematocrit in humans is higher in winter than in summer, and in regions where atmospheric pressure is significantly lower in summer compared to winter, summer decrease in hematocrit is maximal.…”