A label-free ultrasensitive electrochemical DNA sensor based on thin-layer MoS2 nanosheets with high electrochemical activity

Ultrasensitive sensing platform for platelet-derived growth factor BB detection based on layered molybdenum selenide–graphene composites and Exonuclease III assisted signal amplification

“…Thin-layer MoS 2 nanosheets were prepared by Jiao's group via a simple ultrasound exfoliation method from bulk MoS 2 . When evaluated as an electrochemical sensing platform for DNA, the thin-layer MoS 2 nanosheets exhibited wide linear range (1.0 Â 10 À 16 -1.0 Â 10 À 10 M) and low detection limit of 1.9 Â 10 À 17 M (Wang et al, 2015b).…”

A turn-off fluorescent biosensor for the rapid and sensitive detection of uranyl ion based on molybdenum disulfide nanosheets and specific DNAzyme

“…Thus, a turn-off fluorescent biosensor of the rapid, specific and sensitive detection of UO , the substrate-enzyme complex DNAzyme is stable and cannot be effectively adsorbed on the surface of MoS 2 nanosheets since MoS 2 nanosheets have low affinity toward double-strand DNA [24,27]. Therefore, the DNAzyme-MoS 2 nanosheets system showed strong fluorescence intensity.…”

“…Additionally, thin layer 2D MoS 2 nanosheets have more excellent water solubility, more robust mechanical properties and superior electrical performance [25]. In view of the above properties of MoS 2 nanosheet, it has been used for fabricating fluorescent and electrochemical DNA biosensor [24,26,27]. Herein, we developed a high sensitive and selective fluorescent biosensor for UO 2 2+ detection by taking the advantage of uranyl ion-specific DNAzyme and thin layer 2D MoS 2 nanosheets, in hope of providing a reliable and simple method for rapid and on-site detection of UO 2 2+ in aqueous environment to ensure human health.…”

Electrochemical behavior and determination of baicalin on a glassy carbon electrode modified with molybdenum disulfide nano-sheets

“…As 2D layer structures analogous to graphene, thin layer 2D MoS 2 nano-sheets have been reported to have large aspect ratio (surface area to volume), high electrical conductivity, and robust mechanical properties [20]. Owing to their above properties, MoS 2 nano-sheets have been used in fabricating electrochemical DNA biosensors [21,22].…”