A Large Brunner’s Gland Hamartoma Causing Gastrointestinal Bleeding and Obstruction

Nes, L.C.F. de; Ouwehand, F.; Peters, Stefan; Boom, M.J.

doi:10.1159/000111075

Cited by 21 publications

(18 citation statements)

References 12 publications

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“…Treatment is necessary if gastrointestinal bleeding occurs (6)(7)(8)(12)(13)(14), as in the present case. Gastrointestinal bleeding can occasionally be massive and rarely fatal, typically manifested by hematemesis or me-lena, from ulceration or erosion of the mucosa stretched over the submucosal lesion (1,13).…”

Section: Discussionmentioning

confidence: 75%

Brunner’s gland hyperplasia: An unusual cause of gastrointestinal bleeding

Wani

Malik²,

Malik³

et al. 2011

Turk J Gastroenterol

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Brunner's gland hyperplasia is a very rare cause of upper gastrointestinal bleeding. The patient can present with symptoms of gastric outlet obstruction or upper gastrointestinal bleeding requiring prompt surgical or endoscopic intervention. Brunner's gland hyperplasia is an infrequently encountered polypoid lesion in the proximal duodenum. We report this case of Brunner's gland hyperplasia causing upper gastrointestinal bleeding and requiring surgical intervention. CASE REPORTA 40-year-old male patient presented to our Accident and Emergency Department with a complaint of black tarry stools for the last two days. There was no history of smoking or drug intake and no family history. On examination, the patient was grossly pale, ill in appearance, with a pulse of 120/minute and blood pressure of 80/40. Laboratory examination revealed hemoglobin of 5 g/dl, total leukocyte count of 8400/mm 3 and platelet count of 70000/mm 3 . The patient was subjected to upper

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Section: Discussionmentioning

confidence: 75%

Brunner’s gland hyperplasia: An unusual cause of gastrointestinal bleeding

Wani

Malik²,

Malik³

et al. 2011

Turk J Gastroenterol

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“…The most common presentations are obstruction and GI bleeding 1. The symptoms are dependent on the size of the tumour with the chances of obstruction increasing if the size is greater than 2 cm 4. Other presentations may be with gastric outlet obstruction,5 duodenal obstruction and rarely with the intussusception 6–9.…”

Section: Discussionmentioning

confidence: 99%

Brunneroma with duodenojejunal intussusception: a rare cause of gastric outlet obstruction

2013

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“…Surgery is advised for patients with larger pedunculated or sessile Brunner gland hamartomas or when endoscopic interventions fail. Pancreaticoduodenotomy may be required for lesions located in the second portion of the duodenum or when malignancy is suspected (12)(13)(14).…”

Section: Discussionmentioning

confidence: 99%

AIRP Best Cases in Radiologic-Pathologic Correlation: Brunner Gland Hamartoma

Houwers¹,

Bie²,

Hofstee³

2012

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A 68-year-old woman with a 2-month history of nausea and occasional vomiting was referred to the gastroenterologist. The patient complained of vague upper abdominal discomfort that was not influenced by meals. Laboratory findings were normal, and, specifically, no anemia was present (hemoglobin level, 8.4 mmol/L [normal, 7.1-9.9 mmol/L]; hematocrit level, 0.41 [normal, 0.34-0.48]). The patient reported normal bowel movements but mentioned a recent short period of diarrhea. Neither rectal bleeding nor melena was present, and fecal occult blood testing was not performed.A gastroscopy was performed by the gastroenterologist, who noted an extrinsic impression at the greater curvature of the stomach. The pyloric orifice was poorly recognized, and there was suspicion for an intussusception of part of the antrum into the duodenum. Rotation of the proximal part of the duodenum and reduction of the diameter of the duodenal lumen by more than 50% were present as the result of an external mass (Fig 1). The surface of the mass was mostly covered with normal-looking mucosa but became firm and ulcerative more distally. Because of the limited view at gastroscopy, it was difficult to determine whether the duodenal lumen reduction was the result of a submucosal mass or an external invading mass. Several biopsy specimens were obtained from both the normal-appearing mucosa proximal to the narrowed part of the duodenum and the more distal ulcerative surface.

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A Large Brunner’s Gland Hamartoma Causing Gastrointestinal Bleeding and Obstruction

Cited by 21 publications

References 12 publications

Brunner’s gland hyperplasia: An unusual cause of gastrointestinal bleeding

Brunner’s gland hyperplasia: An unusual cause of gastrointestinal bleeding

Brunneroma with duodenojejunal intussusception: a rare cause of gastric outlet obstruction

AIRP Best Cases in Radiologic-Pathologic Correlation: Brunner Gland Hamartoma

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