A Large Cystic Phyllodes Tumor of the Prostate

Abstract

We report a 65 year-old man with a large cystic phyllodes tumor of the prostate. The patient complained of abdominal discomfort and had a soft palpable mass. Computer tomography showed a solid and cystic mass in the pelvic fossa; the mass was adjacent only to the prostate. We excised the mass. Microscopic findings of the mass showed hyperplastic epithelium lined cysts with leaf-like intraluminal epithelia lined stromal projections, less than 2 mitotic counts/10 HPF, low-to-moderated cellularity, and mild-to-moderate cytoplasm atypia. The pathological findings were consistent with a phyllodes tumor of the prostate, a low-grade tumor. Twenty-eight months after the operation, the patient was well with no recurrence or metastases.

Giant multicystic cystadenoma of Cowper's gland: a case report

“…Phylloides tumors of the prostate, also known as prostatic stromal proliferation of uncertain malignant potential are rare lesions with only 82 cases reported according to Bannowsky et al (7). These tumors resemble those found in the mammary glands (6,8). Obstructive symptoms or hematuria are usually found at presentation.…”

“…Most of them present as cystic lesions that can be seen on CT scan and MRI but other presentations, such as polyps, have also been reported (8). Even though they can be classified as benign or malignant, multiple recurrences are frequently found on follow-up; so radical prostatectomy is warranted (6,9). Immunostaining is helpful for diagnosis, being positive for CD34 and desmin (5-7).…”

“…Phylloides tumor, simple prostate cyst, echinococcal cyst, closed syringocele, seminal vesicles cystadenoma, prostate cystadenoma and cystadenocarcinoma, are some of these lesions (3)(4)(5)(6)(7). Assessment with MRI and Computed Tomography (CT) scan can help identify possible etiologies; nevertheless the final diagnosis will be always dependent on final histopatological report.…”

Onset of hydronephrosis and lower urinary tract symptoms in a previously healthy young man: Phyllodes tumour of the prostate as a potential diagnosis.

“…Aguilar and colleagues 3 reported a case of a 67-year-old patient with hematuria secondary to a 900-mL cystic PTP starting from the left base of the prostate. In another case, Chung and colleagues 4 found a cystic PTP of 13.5 cm in diameter weighing 300 g, occupying the whole pelvis and palpable as a soft abdominal mass in a 65-year-old patient. Kawamorita and colleagues 5 described the most striking case -a 55-year-old patient with dysuria affected by a PTP of 60 cm in diameter weighing 8600 g, extending into the retroperitoneum and compressing the bladder, bowel, liver and kidneys.…”

“…Lastly, a correlation between the size of PTP and its grading score was not identified; in our case, the final pathology was diagnosed as a low-grade PTP, as reported by Aguilar and colleagues 3 and Chung and colleagues. 4 …”