A Laser Doppler Blood Flow Measurement System With a 151.4 dBΩ Gain and 0.05% Nonlinearity for PAD Patients

Multi‐vital on‐skin optoelectronic biosensor for assessing regional tissue hemodynamics

“…5 Often, the disease is not noticed until the late stage, when the clinical symptoms are serious; the consequences include amputation, rupture of abdominal aortic aneurysms, renal failure, and so forth. 6,7 At present, the most common methods used to diagnose and monitor PAD are the ankle-brachial index (ABI), 8 oxygen partial pressure (pO 2 ), 9 CT angiography (CTA), 10 and so on; [11][12][13] however, these methods are costly, complex and require highly trained clinicians, especially the pO 2 , which needs the electrode to be inserted into the tissue to measure the local oxygen content. [14][15][16][17] In addition, none of these methods addresses the need to monitor the hemodynamics of patients' distal tissue after discharge.…”

Research progress and clinical application of laser Doppler blood flow measurement technology

“…Its output signal demonstrates a good linear relationship with blood flow, making it convenient for blood flow measurements in conditions such as arterial hypertension [4], burns [5], rosacea [6], and in patients with specific conditions. LDF can also be applied in continuous monitoring of peripheral arterial diseases [7], assessment of hemodynamic effects [8], monitoring of tumor microcirculation indicators [9], pathological studies of periodontitis [10], gingival blood flow measurements [11], and monitoring of microcirculation in critically ill brain conditions [12].…”