A Laser-Doppler-Velocimeter using an optical fiber and its application to local velocity measurement in the coronary artery

Kajiya, Fumihiko; Hoki, Noritake; Tomonaga, Go; Nishihara, Hiroshi

doi:10.1007/bf01989901

Cited by 39 publications

(12 citation statements)

References 7 publications

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“…Since the study on the circulation in the coronary artery and vein by Anrep et al [1,2], there have been reports describing arterial inflow and/or venous outflow [8,9,16,17,22,24]. These reports support Scaramucci's hypothesis, i.e., coronary arterial flow is diastolic predominant, whereas coronary venous flow is systolic predominant.…”

Section: Introductionmentioning

confidence: 58%

Coronary microcirculation in the beating heart

Kajiya

Yada

Hiramatsu

et al. 2008

Med Biol Eng Comput

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The phase opposition of velocity waveforms between coronary arteries (predominantly diastolic) and veins (systolic) is the most prominent characteristic of coronary hemodynamics. This unique arterial and venous flow patterns indicate the importance of intramyocardial capacitance vessels and variable resistance vessels during a cardiac cycle. It was shown that during diastole the intramyocardial capacitance vessels have two functional components, unstressed volume and ordinary capacitance. Unstressed volume is defined as the volume of blood in a vessel at zero transmural pressure. In vivo observation of systolic narrowing of arterioles in mid-wall and in subendocardium indicates the increase in resistance by cardiac contraction.

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Section: Introductionmentioning

confidence: 58%

Coronary microcirculation in the beating heart

Kajiya

Yada

Hiramatsu

et al. 2008

Med Biol Eng Comput

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“…Previous studies have reported that the intramyocardial coronary artery is consistently more predominant in diastole than in systole with or without systolic flow reversal. 29,30) The size of intramyocardial coronaries ranges approximately from 0.4 to 1.5 mm. Using a high frequency transducer, in the black and white images, the axial resolution is about 0.3 to 0.8 mm, and the lateral resolution is 0.8 to 1.1 mm at the depth of 3 cm.…”

Section: Discussionmentioning

confidence: 99%

Novel Method for Assessing Myocardial Perfusion. Visualization and Measurement of Intramyocardial Coronary Blood Flow in the Entire Left Ventricular Wall Using Contrast Enhanced, High Frequency Doppler Echocardiography.

et al. 2001

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SUMMARYUsing a high frequency ultrasonic transducer, intramyocardial coronary blood flow (IM-CBF) can be visualized and evaluated during hemodynamic changes in the anterior wall and septum of the left ventricle (LV). We tested the hypothesis that detection and quantitative measurement of IM-CBF of entire LV segments are feasible using a high frequency ultrasonic transducer in conjunction with intravenous contrast injection in vivo.A 3 -8 MHz transducer was used to image and measure IM-CBF in 10 anesthetized dogs. We obtained a color Doppler image of IM-CBF in the LV short-axis view after intravenous Levovist(TM) injection (25 mg / ml). The IM-CBF velocity was recorded using spectral Doppler in the antero-septal and infero-posterior wall of closed chest dogs and in the entire LV after opening the chest. A significant increase in IM-CBF velocity was observed in all LV regions after adenosine 5'-triphosphate (ATP) administration. After Levovist(TM) injection, the visualization of IM-CBF was improved and the spectral Doppler pattern of coronary flow velocity was clarified compared to baseline. IM-CBF was assessed in the antero-septal region of the LV before and after left anterior descending coronary artery occlusion.A high frequency ultrasonic transducer in conjunction with intravenous contrast injection improved IM-CBF visualization, enabling quantitative evaluation of the intramyocardial coronary circulation in the entire LV after coronary occlusion and hyperemia. This study may represent a step towards noninvasive assessment of myocardial perfusion before and after coronary reperfusion. (Jpn Heart J 2001; 42: 101-113)

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“…The principle and optical arrangements of our system have been described in our previous publications [11][12][13][14]. In brief, a linearly polarized He-Ne laser beam (frequency: fo, wave length: 632.8nm) is divided into incident and reference beams by a beam splitter (Fig.…”

Section: Optical Arrangement Of the Laser Doppler Velocimeter With Anmentioning

confidence: 99%

“…In order to apply the laser Doppler velocimeter to real-time observation of phasic blood flow velocity, we developed a laser Doppler velocimeter using an optical fiber [11][12][13][14]. The fiber delivers light into a vessel and collects the scattered light from the moving erythrocytes through the same fiber.…”

Section: Coronary Vein Flow Velocity -Coronary Flow Reservementioning

confidence: 99%

A laser Doppler catheter for monitoring both phasic and mean coronary vein flow

et al. 1990

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A new catheter-type laser Doppler velocimeter has been developed to monitor coronary vein flow. A thin graded-index multimode optical fiber (outer diameter of 125 microns) is set inside a 5-F catheter, and eight elastic silicon rubber spikes are arranged radially toward the vessel wall to fix the catheter tip in or near the axial region of the coronary vein. He-Ne laser light (wave length = 632.8nm) is introduced into the blood through the optical fiber, and reflected light is collected by the same fiber. The Doppler signal is detected by a spectrum analyzer. To avoid any effect by the spikes on flow, the fiber is extended from the catheter tip by 3 mm at the time of measurement. Straight and curved tubing was used to examine the accuracy of flow measurement. The flow velocities recorded by the catheter, which were measured by an electromagnetic flowmeter, exhibited excellent linearity (r = straight; 0.982, curved: 0.996). The blood flow velocity in the great cardiac vein was measured by this method in five dogs. The predominantly systolic waveform, which is a characteristic of the coronary vein flow, was observed in all of the dogs. The great cardiac vein velocity increased around the beginning of the ventricular ejection and decreased gradually after the peak formation at mid- or end-diastole. In addition to this main peak, small flow components were frequently observed during isovolumic contraction and the atrial contraction phase, although these flow components varied in individual dogs. Following left anterior descending artery occlusion, the great cardiac vein flow velocity decreased significantly.(ABSTRACT TRUNCATED AT 250 WORDS)

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A Laser-Doppler-Velocimeter using an optical fiber and its application to local velocity measurement in the coronary artery

Cited by 39 publications

References 7 publications

Coronary microcirculation in the beating heart

Coronary microcirculation in the beating heart

Novel Method for Assessing Myocardial Perfusion. Visualization and Measurement of Intramyocardial Coronary Blood Flow in the Entire Left Ventricular Wall Using Contrast Enhanced, High Frequency Doppler Echocardiography.

A laser Doppler catheter for monitoring both phasic and mean coronary vein flow

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