For a modern e-Learning platform, it has to confront with an important issue that is how to provide meaningful learning for learners. In this paper, we used the method of concept maps to integrate the four tiers, which are knowledge management, instructional, learning and technological tier, in order to achieve the meaningful learning. The significance of concept maps is not only on the promotion of knowledge concepts and action skills, but also on the affection which can be rendered the right cognition and values for learners. Finally, this research proposed a Knowledge Management Learning System (KMLS), where it can support learning-process progress and facilitate learners' learning more meaningfully.