A life-threatening duodenal ulcer hemorrhage due to previously unknown primary hyperparathyroidism

Abstract

Peptic ulcer bleeding due to primary hyperparathyroidism is extremely rare. We report a case of a 42-year-old male with life-threatening acute upper gastrointestinal bleeding secondary to a duodenal ulcer and a history of kidney stones. Gastroscopic therapy, Billroth II gastrointestinal anastomosis and angiographic embolization were sequentially conducted to arrest the hemorrhage. A complete investigative work-up revealed that the duodenal ulcer bleeding was due to primary hyperparathyroidism coexisting with a parathyroid adenoma. Following this event, the patient developed a severe abdominal cavity infection and sepsis. An elective parathyroidectomy was performed, and the histology was confirmed to be a typical parathyroid adenoma. Postoperatively, the patient’s calcium and parathyroid levels were normalized. Attention should be paid to patients with an upper gastrointestinal ulcer, especially when it is accompanied by kidney stones.

Clinical descriptive analysis of severe Pneumocystis jirovecii pneumonia in renal transplantation recipients

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Stones, Bones, Groans, and Psychic Moans: Primary Hyperparathyroidism Presenting as Surgical Emergency

“…The diagnosis is usually established by routine biochemical testing as patients remain symptom-free initially. Peptic ulcer disease due to hyperparathyroidism is rare and has been described in only a few case reports [2-4]. Most patients with PHPT are cured with parathyroidectomy.…”