A Literature Review—&amp;lt;i&amp;gt;Khaya senegalensis, Anacardium ouest&amp;lt;/i&amp;gt; L., &amp;lt;i&amp;gt;Cassia sieberiana&amp;lt;/i&amp;gt; DC., &amp;lt;i&amp;gt;Pterocarpus erinaceus&amp;lt;/i&amp;gt;, &amp;lt;i&amp;gt;Diospyros mespiliformis&amp;lt;/i&amp;gt;, &amp;lt;i&amp;gt;Ocimum gratissimum&amp;lt;/i&amp;gt;, &amp;lt;i&amp;gt;Manihot esculenta&amp;lt;/i&amp;gt;, &amp;lt;i&amp;gt;Vernonia amygdalina&amp;lt;/i&amp;gt; Delile, &amp;lt;i&amp;gt;Pseudocedrela kotschyi&amp;lt;/i&amp;gt; and &amp;

Dougnon, Victorien; Hounsa, Edna; Koudokpon, Hornel; Lègba, Boris; Fabiyi, Kafayath; Sintondji, Kévin; Afaton, Anny; Akouta, Merveille; Klotoé, Jean Robert; Bankolè, Honoré; Baba-Moussa, Lamine; Dougnon, Jacques

doi:10.4236/abb.2020.1110031

Cited by 9 publications

(8 citation statements)

References 48 publications

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“…This study was aimed at providing scientific data on the mechanism of action of the antibacterial effect of Khaya senegalensis, Anacardium occidentale L., Cassia sieberiana DC., Pterocarpus erinaceus, Diospyros mespiliformis, Ocimum gratissimum, Manihot esculenta, Vernonia amygdalina Delile, Pseudocedrela kotschyi, and Daniellia oliveri. These plants are among the most widely used medicinal plants in the management of infectious diarrhea in West Africa [8].…”

Section: Discussionmentioning

confidence: 99%

“…Plant Material. The plant material consists of 10 medicinal plants used in the traditional treatment of infectious diarrhea in West Africa [8]. The characteristics of each medicinal plant are presented in Table 1.…”

Section: Methodsmentioning

confidence: 99%

“…Khaya senegalensis, Anacardium ouest L., Cassia sieberiana DC., Pterocarpus erinaceus, Diospyros mespiliformis, Ocimum gratissimum, Manihot esculenta, Vernonia amygdalina Delile, Pseudocedrela kotschyi, and Daniellia oliveri are among the most widely used medicinal plants in the management of infectious diarrhea in West Africa [8]. Numerous scientific works have been carried out to enhance their value, notably through the determination of their antibacterial activity.…”

Section: Introductionmentioning

confidence: 99%

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Percentage Destabilization Effect of Some West African Medicinal Plants on the Outer Membrane of Various Bacteria Involved in Infectious Diarrhea

Dougnon

Hounsa

Agbodjento

et al. 2021

BioMed Research International

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Previous work stated that Khaya senegalensis, Anacardium ouest L., Pterocarpus erinaceus, Diospyros mespiliformis, Ocimum gratissimum, Manihot esculenta, Vernonia amygdalina Delile, and Daniellia oliveri have a great potential for the fight against infectious diarrhea. However, data on their antibacterial activity on strains of bacteria responsible for infectious diarrhea are not available. This study is aimed at elucidating the mechanism of action of the antibacterial effect of these plants on some bacterial strains responsible for diarrheal infections. The design of the study included first evaluating the degree of sensitivity of Salmonella typhimurium 14028, Escherichia coli ATCC 25922, Shigella spp., and Salmonella spp. strains to aqueous and hydroethanolic extracts of each plant, followed by the determination of minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and antibiotic power (Pa). This screening was completed with the evaluation of the possible mode of action of the extracts by testing the membrane permeability of these bacterial strains. The data collected indicate that the bacterial strains tested were sensitive to the extracts to varying degrees, except Cassia sieberiana DC and Pseudocedrela kotschyi extracts. For the active extracts, inhibition diameters ranged from 18.33 mm to 7 mm. With the exception of Escherichia coli, all strains were sensitive to the aqueous and hydroethanolic extracts of Anacardium occidentale. MICs vary between 3.37 and 25 mg/ml. Membrane permeability test data show that all active extracts affect the bacterial strains tested by attacking the stability of their outer membrane. For all active extracts, the high percentage of membrane destabilization of the bacteria is significantly ( p < 0.05 ) better than that of cefixime used as a reference. Thus, it appears that these extracts can destroy Gram-negative bacteria and increase the fluidity and permeability of their cytoplasmic membrane. The knowledge of the mechanism of action of these extracts is an interesting contribution to the fundamental knowledge on the alternative that medicinal plants represent to antibiotics. These extracts can be used in the management of infectious diarrhea.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Percentage Destabilization Effect of Some West African Medicinal Plants on the Outer Membrane of Various Bacteria Involved in Infectious Diarrhea

Dougnon

Hounsa

Agbodjento

et al. 2021

BioMed Research International

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“…The active substances or secondary metabolite compounds contained in plant extracts can have physiological a n d p h a r m a c o l o g i c al e ff e c t s on h um a n s (2 ). The ethnopharmacological use of plants involved in the treatment of various diarrheal diseases has been reported by previous studies (3). Among these plants, Diospyros mespiliformis and Anacardium occidentale are known for their involvement in the treatment of infectious diarrhea and malaria (4,5).…”

Section: Introductionmentioning

confidence: 93%

“…The powders obtained were identified and stored in plastic vials at room temperature in the laboratory. From this powder, two types of extraction of each of the medicinal plants studied were carried out, following the methodology described by Legba et al (2020) (20) for aqueous extraction and hydroethanolic extraction (50% water-ethanol; v/v). Briefly, fifty (50) grams of powder was macerated in 500 mL of solvent (water and waterethanol).…”

Section: Preparation Of Extractsmentioning

confidence: 99%

Fetotoxicity and Subacute Toxicity of Some Plants Involved in the Treatment of Infectious Diarrhea in Benin

Hounsa¹,

Dougnon²,

Agbankpé³

et al. 2022

Front. Trop. Dis

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This study aimed to provide data on the subacute toxicity and fetotoxicity of aqueous and hydroethanolic extracts of Daniellia oliveri (Rolfe) Hutch. & Dalziel, Anacardium occidentale L., Diospyros mespiliformis Hochst. ex A. DC., Khaya senegalensis (Desv.) A. Juss., Ocimum gratissimum L., Vernonia amygdalina Delile, Pterocarpus erinaceus Poir., and Manihot esculenta Crantz used in the treatment of diarrheal diseases in Benin. For subacute toxicity, each male and female Wistar rat received by esophageal gavage a maximum of 1000 mg/kg over 28 days following the Organization for Economic Co-operation and Development (OECD) Guideline No. 407. Bodyweight changes, biochemical and hematological parameters were assessed. The fetotoxicity of the extracts was evaluated on Dutch Blue hen eggs at 100 mg/kg and 300 mg/kg. The hatching rate, biochemical and hematological constants were subsequently determined. The subacute toxicity data did not indicate any mortality or signs of toxicity. Also, no significant difference in the bodyweight of the rats and the hematological parameters was noted. Concerning fetotoxicity, a low hatching rate (varying from 20% to 50%) was observed in the batches treated with the extracts at 300mg/kg compared to the rate obtained in the negative control batch (80%). The batches that received the hydroethanolic extracts of Vernonia amygdalina and Manihot esculenta at the tested doses had a hatching rate of 0%. When looking at hematological parameters, no significant difference was noted for all batches. However, an increase in the Aspartate Amino-Transferase (ASAT) values was noted in the batches that received the hydroethanolic extract of Khaya senegalensis and the aqueous extract of Diospyros mespiliformis at 100 and 300 mg/kg. These results explicitly show that the hydroethanolic extracts of Manihot esculenta and Vernonia amygdalina are fetotoxic at the tested doses.

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In-vitro antioxidant, lipoxygenase inhibitory, and in-vivo muscle relaxant potential of the extract and constituent isolated from Diospyros kaki (Japanese Persimmon)

Mujawah

Bawazeer

Wadood

et al. 2023

Heliyon

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A Literature Review—<i>Khaya senegalensis, Anacardium ouest</i> L., <i>Cassia sieberiana</i> DC., <i>Pterocarpus erinaceus</i>, <i>Diospyros mespiliformis</i>, <i>Ocimum gratissimum</i>, <i>Manihot esculenta</i>, <i>Vernonia amygdalina</i> Delile, <i>Pseudocedrela kotschyi</i> and &

Cited by 9 publications

References 48 publications

Percentage Destabilization Effect of Some West African Medicinal Plants on the Outer Membrane of Various Bacteria Involved in Infectious Diarrhea

Percentage Destabilization Effect of Some West African Medicinal Plants on the Outer Membrane of Various Bacteria Involved in Infectious Diarrhea

Fetotoxicity and Subacute Toxicity of Some Plants Involved in the Treatment of Infectious Diarrhea in Benin

In-vitro antioxidant, lipoxygenase inhibitory, and in-vivo muscle relaxant potential of the extract and constituent isolated from Diospyros kaki (Japanese Persimmon)

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