A logic model for precision medicine implementation informed by stakeholder views and implementation science

Chanfreau‐Coffinier, Catherine; Peredo, Jane; Russell, Marcia M.; Yano, Elizabeth M.; Hamilton, Alison B.; Lerner, Barbara; Provenzale, Dawn; Knight, Sara J.; Voils, Corrine I.; Scheuner, Maren T.

doi:10.1038/s41436-018-0315-y

Cited by 27 publications

(43 citation statements)

References 18 publications

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“…(5) multiple CT scans are needed during the operation, and the radiation damage to patients and surgical staff is inevitable and can not be ignored, so we should communicate with patients before operation. (6) this study is a retrospective clinical study, which needs to be further explored by randomized controlled trials.…”

Section: Discussionmentioning

confidence: 99%

“…To address this problem, a hybrid operating room (HOR) with computed tomography (CT) can be used to further delineate the surgical correction. We evaluated our experience using the HOR with CT-assisted and non-CT assisted patients in the treatment of type A3 burst fractures with neurologic symptoms with the goal of assessing the efficacy of individualizing precise surgical treatment for each patient [6,7].…”

Section: Introductionmentioning

confidence: 99%

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Efficacy of Computed Tomography-assisted Limited Decompression in the Surgical Management of Thoracolumbar Fractures With Neurological Deficit

Shi

Chou

Wang

et al. 2021

Preprint

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Objective: to investigate the effect of CT-assisted limited decompression in the management of single segment A3 lumbar burst fracture. Method: A retrospective study of 106 cases with a single-level Magerl type A3 lumbar burst fractures treated with short-segment posterior internal fixation and limited decompression from January 2015 to June 2019 was performed. Patients were divided into two groups: CT-assisted and non-CT-assisted. Perioperative factors, clinical outcomes, postoperative complications, imaging parameters and health-related quality of life (HRQoL) were evaluated. Results: There was no significant difference between the two groups in the kyphosis, anterior vertebral body height loss, posterior vertebral body height loss, operative time, and postoperative complications. The visual analogue score (VAS) and spinal canal encroachment in the CT-assisted group were lower than those in the non-CT-assisted group (P < 0.05). The Japanese Orthopaedic Association score (JOA), the simplified HRQoL scale and American Spinal Injury Association (ASIA) Spinal Cord Injury Grade in the CT-assisted group were higher than those in the non-CT-assisted group (P < 0.05).Conclusion: CT-assisted limited decompression in the treatment of single-segment A3 lumbar burst fracture can achieve better fracture reduction and surgical results, and improve the long-term recovery of neurological function and quality of life of the patients.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Efficacy of Computed Tomography-assisted Limited Decompression in the Surgical Management of Thoracolumbar Fractures With Neurological Deficit

Shi

Chou

Wang

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…Logic models are well established in general service design and implementation literature, but are under-utilised in healthcare services where they are predominantly used to describe the establishment of new services. 18,19 In comparison, there are fewer examples of the use of logic models to facilitate the wider scale-up of established services. Two such programmes are described in the literature; the World Health Organization / Centers for Disease Control and Prevention's vitamin and mineral interventions in public health project and the Ensemble, Prévenons l'Obésité Des Enfants' (EPODE) [Together let's Prevent Childhood Obesity] programme, the latter of which developed a model retrospectively after already spreading to 500 centres.…”

Section: Discussionmentioning

confidence: 99%

Scaling up perioperative medicine for older people undergoing surgery (POPS) services; use of a logic model approach

et al. 2019

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Perioperative medicine for older people undergoing surgery (POPS) services are gaining traction, in acknowledgment of the poorer outcomes experienced by older surgical patients. In response to the NHS' growing focus on scaling innovation, a logic model of the POPS service at Guy's and St Thomas' NHS Foundation Trust was developed to articulate a founding centre's experience. The logic model was applied as a means of service evaluation and to guide implementation of a new POPS service at a district general trust. This is a novel study within the fi eld of perioperative medicine for older people, interlinking implementation science theory to achieve meaningful clinical results and describe the lessons learnt during the process. Future work will include validation of this logic model to facilitate national POPS scale-up.

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“…Chanfreau-Coffinier et al ( 2019 ) provided a helpful illustration of how precision medicine could be implemented. They convened a conference of 80 Veterans Affairs stakeholders to develop a detailed logic model that can be used by an organization planning to introduce precision medicine.…”

Section: An Introduction To Artificial Intelligence (Ai) and Precisiomentioning

confidence: 99%

Improving Mental Health Services: A 50-Year Journey from Randomized Experiments to Artificial Intelligence and Precision Mental Health

Bickman

2020

Adm Policy Ment Health

111

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This conceptual paper describes the current state of mental health services, identifies critical problems, and suggests how to solve them. I focus on the potential contributions of artificial intelligence and precision mental health to improving mental health services. Toward that end, I draw upon my own research, which has changed over the last half century, to highlight the need to transform the way we conduct mental health services research. I identify exemplars from the emerging literature on artificial intelligence and precision approaches to treatment in which there is an attempt to personalize or fit the treatment to the client in order to produce more effective interventions. Keywords Mental health services • Artificial intelligence • Machine learning • Precision mental health • Randomized clinical trials (RCTs) • Precision medicine "AI will bring many wonders. It may also destabilize everything from nuclear détente to human friendships. We need to think much harder about how to adapt... it is changing human knowledge, perception and reality-and, in so doing, changing the course of human history. We seek to understand it and its consequences and encourage others across the disciplines to do the same."-Kissinger et al. 2019, pp. 24-26 "AI is one of the most profound things we're working on as humanity. It's more profound than fire or electricity."-Alphabet CEO Sundar Pichai, in Thompson and Bodoni 2020. This article is part of a special issue, Festschrift for Leonard Bickman: The Future of Children's Mental Health Services.

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A logic model for precision medicine implementation informed by stakeholder views and implementation science

Cited by 27 publications

References 18 publications

Efficacy of Computed Tomography-assisted Limited Decompression in the Surgical Management of Thoracolumbar Fractures With Neurological Deficit

Efficacy of Computed Tomography-assisted Limited Decompression in the Surgical Management of Thoracolumbar Fractures With Neurological Deficit

Scaling up perioperative medicine for older people undergoing surgery (POPS) services; use of a logic model approach

Improving Mental Health Services: A 50-Year Journey from Randomized Experiments to Artificial Intelligence and Precision Mental Health

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