this is a causative factor in DHF. We investigated the association between heart rate and postprocedural DHF in patients undergoing AF ablation.
Methods
PatientsThe data of a total of 1,004 consecutive patients undergoing initial ablation for AF at the Kansai Rosai Hospital Cardiovascular Center between December 2014 and December 2018 were analyzed retrospectively. Exclusion criteria were age <20 years and incomplete standard electrophysiological studies following pulmonary vein (PV) isolation.This study complied with the Declaration of Helsinki and the ethical standards of the Kansai Rosai Hospital Cardiovascular Center on human experimentation. Written informed consent for catheter ablation and the use of data in this study was obtained from all patients, and the study protocol was approved by the Kansai Rosai Hospital Institutional Review Board (Reference no. 2001030).
Catheter ablation is one of several well-established therapies for atrial fibrillation (AF), but is a complex interventional procedure that is associated with a significant risk of complications. 1 A previous study showed an overall incidence of complications of 6.3%. 2 Decompensated heart failure (DHF) can occur after catheter ablation. 3 Previous studies showed that 20-26% of patients undergoing AF ablation suffered symptoms of heart failure within 30 days after the procedure. 4,5There is a wide variety of risk factors for DHF, such as overhydration, tachycardia, bradycardia, and blood pressure elevation. 6 Fluid load from irrigated catheters, sedation, and chemotactic invasion may also cause DHF after catheter ablation. 4 Cardiac output is also known to decrease in more than one-third of patients after cardioversion of AF, recovering by degrees over 4 weeks. 7 Bradycardia and sinus node dysfunction sometimes occur after persistent AF ablation, and bradycardia generally causes a decrease in cardiac output. 8,9 Accordingly, we hypothesized that cardiac output cannot be compensated for by a decrease in heart rate after the procedure, and that