2014
DOI: 10.2337/dc14-0186
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A Low–Glycemic Index Meal and Bedtime Snack Prevents Postprandial Hyperglycemia and Associated Rises in Inflammatory Markers, Providing Protection From Early but Not Late Nocturnal Hypoglycemia Following Evening Exercise in Type 1 Diabetes

Abstract: OBJECTIVETo examine the influence of the glycemic index (GI) of foods consumed after evening exercise on postprandial glycemia, metabolic and inflammatory markers, and nocturnal glycemic control in type 1 diabetes. RESEARCH DESIGN AND METHODSOn two evenings (∼1700 h), 10 male patients (27 6 5 years of age, HbA 1c 6.7 6 0.7% [49.9 6 8.1 mmol/mol]) were administered a 25% rapid-acting insulin dose with a carbohydrate bolus 60 min before 45 min of treadmill running. At 60 min postexercise, patients were administe… Show more

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Cited by 56 publications
(76 citation statements)
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“…The benefits of isomaltulose on fat oxidation, metabolic control, and incidences of hypoglycemia during physical activity in men with type 1 diabetes mellitus has been the focus of research by the group of Bracken. Isomaltulose consumption during moderate carbohydrate loading before exercise improved glycemic control and protected against hypoglycemia, while maintaining running performance [30,31,36,38]. …”
Section: Sports Nutrition and Cognitive Performancementioning
confidence: 99%
“…The benefits of isomaltulose on fat oxidation, metabolic control, and incidences of hypoglycemia during physical activity in men with type 1 diabetes mellitus has been the focus of research by the group of Bracken. Isomaltulose consumption during moderate carbohydrate loading before exercise improved glycemic control and protected against hypoglycemia, while maintaining running performance [30,31,36,38]. …”
Section: Sports Nutrition and Cognitive Performancementioning
confidence: 99%
“…About 150 μl of at least 6-hour fasting capillary whole blood specimen was collected and the fasting time was recorded. Blood glucose level was immediately measured on an automatic analyzer (Biosen C-line; EKF Diagnostic GmbH, London, U.K.)48. Hyperglycemia was defined as more than the 90 th percentiles of fasting glucose.…”
Section: Methodsmentioning
confidence: 99%
“…Exercício físico, dieta e suplementação Em relação à dieta em conjunto com a prática de atividade física, Campbell et al 20 averiguaram que consumir alimentos com baixo índice glicêmico e com a redução da dose de insulina de ação rápida pós-exercício (50%) impede a hiperglicemia pós-prandial, diminui a presença de marcadores metabólicos e inflamatórios e, além disso, fornece proteção sobre hipoglicemia em até oito horas pós-exercício. Entretanto, o risco de hipoglicemia noturna ainda permanece.…”
Section: Página 9 De 14unclassified
“…Esse quadro tem estimulado diversas estatégias para manter as taxas glicêmicas dentro da normalidade, sobretudo em ensaios cujos pacientes utilizam bombas de insulina e os chamados "pâncreas artificiais" [9][10][11][12][13] . Existe também preocupação em relação à diminuição e, até mesmo, suspensão das doses de insulina pré e pós-exercício para evitar danos causados por esses episódios [14][15][16][17][18] e também relacionado ao índice glicêmico dos alimentos 19,20 . É bastante discutida na literatura científica os efeitos do EF aeróbico, de diferentes intensidades, de forma direta ou indireta, para comparar os seus efeitos em diversas variáveis.…”
Section: Introductionunclassified