“…And so it should be, it must be: Charles Darwin knew already that it is neither the strongest nor the most intelligent species that survive, but the ones responsive to change (Megginson 1963). And change we did: From the origins of physiology around 350 B.C.E., when Aristotle described the indispensable relation of structure and function in all things living, to the professional image of Catherine de'Medicis physician Jean Fernel coining the term 'physiologist' almost two millennia later (Gordetsky et al 2009), from the avalanche-like accumulation of physiological knowledge that started in the 1800s (Larsen et al 2011, Persson 2012b, Stj€ arne & Persson 2012) to modern-day molecular studies being confirmed in vivo with utmost care and respect for the living (Persson & Henriksson 2011, Westerhof 2011) and careful, conscious interpretation (Bie 2012). Our work has crossed borders between countries, cultures and disciplines, every day, and forms an important part of the foundations of the modern-day knowledge-based society (Persson 2012d).…”