In order to solve the application of driving motor drive structure and sensor technology in logistics vehicles to make the logistics vehicles adapt to more complex road conditions, a research on logistics vehicle based on electronic differential speed is presented, and its mechanical structure and automatic control system are designed. Firstly, the hub motor, mechanical structure, automatic controller, electronic differential principle, and fuzzy PI control theory of intelligent logistics vehicle are introduced. Besides, the hub motor, mechanical structure and automatic controller are designed. For the design of hub motor, the drive motor is chosen as brushless direct current (DC) motor. In the mechanical structure, three kinds of wheel structure are introduced, and the four-wheel structure is selected. The Intelligent Power Module (IPM) of IKCM30F60GA driving circuit is designed for the automatic controller. Then, the vehicle control strategy based on electronic differential velocity model system master control module algorithm is constructed. Finally, an external hub motor is constructed for finite element simulation, and the experiment is carried out for no-load, load and electronic differential steering of the external rotor. The experimental results show that the brushless DC motor is in the form of four wheels. The mechanical structure of the wheel is that the first two wheels are driving wheels and the two rear wheels are directional wheels. According to the simulation experiment, fuzzy PI has a shorter response time, stronger anti-interference and stability than conventional PI. The logistics vehicle based on electronic differential speed designed in this research can adapt to more complex road conditions, and the degree of intelligence and automation has been improved. The research provides a good guiding ideology for the development of logistics vehicles in the e-commerce industry.