2022
DOI: 10.3389/fphy.2022.886193
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A Mechano-Chemical Computational Model of Deep Vein Thrombosis

Abstract: Computational models of deep vein thrombosis (DVT) typically account for either the mechanical or biochemical factors involved in thrombus formation. Developing a model that accounts for both factors will improve our understanding of the coagulation process in this particular disease. The work presented in this study details the development of a CFD model that considers the biochemical reactions between thrombin and fibrinogen, pulsatile blood flow, and clot growth within a three-dimensional patient-specific c… Show more

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Cited by 2 publications
(1 citation statement)
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“…Significant advances in computing technology have improved the approximation of solutions for the Navier-Stokes equations, which describe fluid flow in a wide range of contexts [57][58][59][60][61][62][63][64][65][66][67]. As a result, CFD models have been developed for a plethora of applications, including biofluid flows [68][69][70][71]. The solvers compute pressure and velocity results, which can then be used to calculate quantities such as shear stress.…”
Section: Introductionmentioning
confidence: 99%
“…Significant advances in computing technology have improved the approximation of solutions for the Navier-Stokes equations, which describe fluid flow in a wide range of contexts [57][58][59][60][61][62][63][64][65][66][67]. As a result, CFD models have been developed for a plethora of applications, including biofluid flows [68][69][70][71]. The solvers compute pressure and velocity results, which can then be used to calculate quantities such as shear stress.…”
Section: Introductionmentioning
confidence: 99%