A Meta-Analysis of Observational Intra-Arterial Stroke Therapy Studies Using the Merci Device, Penumbra System, and Retrievable Stents

Abstract

BACKGROUND AND PURPOSE:The time from arterial puncture to successful recanalization is an important milestone toward timely recanalization. With the significant improvement in recanalization rates by using thrombectomy devices, procedural time to recanalization is becoming a determinant factor in choosing among available devices. We aimed to assess the impact of time to recanalization on the outcome of intra-arterial stroke therapies.

Impact of Age and Baseline NIHSS Scores on Clinical Outcomes in the Mechanical Thrombectomy Using Solitaire FR in Acute Ischemic Stroke Study

“…The relatively high rates of successful revascularization are unable to improve the number of patients with favorable clinical outcomes. 12 This result might be explained, at least in part, by inappropriate patient selection for endovascular interventions. The SPAN-100 index is promising to provide a simple and readily available tool to enhance the patient-selection process.…”

Acute Ischemic Stroke

“…[42][43][44][45] Recently, stentrievers have been demonstrated to improve functional outcomes compared with either IA-tPA or Merci Retriever. 46 This suggests a direct translation from technical success to clinical success.…”

Effect of Retrievable Stent Size on Endovascular Treatment of Acute Ischemic Stroke: A Multicenter Study

“…11 This device was at first designed for aneurysms, with a variety of diameters made available to meet the needs of different sizes of intracranial vessels. 12 For mechanical thrombectomy, stents with 4-and 6-mm diameters delivered through 0.021-and 0.027-inch microcatheters, respectively, optimize performance in intracranial large vessels in present day interventional therapy.…”