1990
DOI: 10.1002/jab.770010305
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A method for preparation of etched collagen fibers that support neurite outgrowth

Abstract: Use of collagenous substrates for growth of attachment-dependent and attachmentindependent cells have been reported in the literature. Growth of fibroblasts and epithelial cells on collagen sponges and fibers has been previously studied in our laboratory. This article reports the result of studies of neurite outgrowth on etched collagen fibers in cell culture. Collagen fibers with a mean diameter of about 134 p m were etched on glass coverslips using a collagenase solution until individual fibrils of 1 p m in … Show more

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