With the rapid development of UAV technology, the research topic of remote sensing image segmentation has gradually attracted more and more attention. Whether the image can be accurately segmented is a measure of the goodness of the algorithm. In recent years, machine learning methods have been applied to a large number of fields, and deep neural network technology has also been widely used in the field of UAV remote sensing image segmentation. This paper introduces the specific applications of various deep learning methods in remote sensing image segmentation, and briefly analyzes the development of neural networks in this problem according to the research status of several typical deep neural networks in UAV remote sensing image segmentation. Research shows that on the basis of proper adjustment of optimizer, learning rate and loss function, using deep learning method to segment UAV remote sensing images, the accuracy rate can reach more than 96%.