Artificial Intelligence (AI) applications streamline workflows, automate tasks, and require adaptive strategies for effective integration into business processes. This research explores the transformative influence of AI on various industries, such as software engineering, automation, education, accounting, mining, legal services, and media. We investigate the relationship between technological advancements and the job market to identify relevant skills for individuals and organizations for implementing and managing AI systems and human–machine interactions necessary for actual and future jobs. We focus on the essential adaptations for individuals and organizations to flourish in this era. To bridge the gap between AI-driven demands and the existing capabilities of the workforce, we employ the Rapid Review methodology to explore the integration of AI in businesses, identify crucial skill sets, analyze challenges, and propose solutions in this dynamic age. We searched the Scopus database, screening a total of 39 articles, of which we selected 20 articles for this systematic review. The inclusion criteria focused on conference papers and journal articles from 2020 or later and written in English. The selected articles offer valuable insights into the impact of AI on education, business, healthcare, robotics, manufacturing, and automation across diverse sectors, as well as providing perspectives on the evolving landscape of expertise. The findings underscore the importance of crucial skill sets, such as technical proficiency and adaptability, to successfully adopt AI. Businesses respond strategically by implementing continuous skill adaptation and ethical technology to address challenges. The paper concludes by emphasizing the imperative of balanced skill development, proactive education, and strategic integration to navigate the profound impact of AI on the workforce effectively.