A mitochondria-targeted fluorescent probe for real-time imaging SO2/H2O2

Wang, Yan; Chen, Ru-Xing; Tian, Rui; Li, Yan; Guo, Zongxia; Fang, Ying; Zhang, Qi; Chen, Shaojin; Wang, Kunpeng; Hu, Zhi‐Qiang

doi:10.1016/j.saa.2021.120134

Cited by 24 publications

(1 citation statement)

References 41 publications

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“…The authors have cited an additional reference within the Supporting Information. [39][40][41][42][43]…”

Section: Supporting Informationmentioning

confidence: 99%

A Mitochondria‐Targeted Fluorescent and Colorimetric Probe for Sulfur Dioxide Derivatives and Hydrogen Peroxide in Live Cells

Zhou,

Zhang,

Tang

et al. 2023

ChemPhotoChem

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The abnormal fluctuations of sulfur dioxide (SO2) and its derivatives are closely associated with various physiology and pathological progresses in biological system. Herein, we have developed two fluorescent and colorimetric probes (1 and 2) based on hemicyanine dye for the detection of SO2 derivatives and hydrogen peroxide (H2O2) in vitro and live cells. The response mechanisms involve SO2 derivatives mediated nucleophilic addition reaction to the double bond and subsequent H2O2 promoted elimination of bisulfite. Besides having excellent photophysical properties, probe 1 with higher fluorescence efficiency is further applied for live cells imaging, indicating that it can solely accumulate into mitochondria and track SO2 derivatives and H2O2 in live cells.

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“…The authors have cited an additional reference within the Supporting Information. [39][40][41][42][43]…”

Section: Supporting Informationmentioning

confidence: 99%

A Mitochondria‐Targeted Fluorescent and Colorimetric Probe for Sulfur Dioxide Derivatives and Hydrogen Peroxide in Live Cells

Zhou,

Zhang,

Tang

et al. 2023

ChemPhotoChem

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Design of Dual‐responsive ROS/RSS Fluorescent Probes and Their Application in Bioimaging

Huang

Yue

Yin

et al. 2022

Chemistry An Asian Journal

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Intracellular redox homeostasis exerts a tremendous influence on pathophysiological fields. In order to maintain the homeostasis of intracellular redox state, reactive oxygen species (ROS) and reactive sulfur species (RSS) react and transform with each other, and their levels also directly reflect the degree of oxidative stress and disease. To understand the correlation and pathophysiological effects of these two signaling molecules in oxidative stress, unique fluorescence imaging tools are required. Fluorescent probes have become an indispensable detection tool in modern scientific research and disease diagnosis. Currently, there are many fluorescent probes for detecting ROS or RSS. However, the cellular environment is extremely complex. Dual detection fluorescent probes that can monitor more than one species in a biological environment cause our attention. This review describes dual detection fluorescent probes that can detect ROS and RSS simultaneously or sequentially. This will provide strong support for the study of redox homeostasis.

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Enhancing probe’s sensitivity for peroxynitrite through alkoxy modification of dicyanovinylchromene

Fang

Wang

et al. 2022

Anal Bioanal Chem

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A mitochondria-targeted fluorescent probe for real-time imaging SO2/H2O2

Cited by 24 publications

References 41 publications

A Mitochondria‐Targeted Fluorescent and Colorimetric Probe for Sulfur Dioxide Derivatives and Hydrogen Peroxide in Live Cells

A Mitochondria‐Targeted Fluorescent and Colorimetric Probe for Sulfur Dioxide Derivatives and Hydrogen Peroxide in Live Cells

Design of Dual‐responsive ROS/RSS Fluorescent Probes and Their Application in Bioimaging

Enhancing probe’s sensitivity for peroxynitrite through alkoxy modification of dicyanovinylchromene

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