Vehicle antilock systems play a very important role in the stability and reliability during vehicle braking. Due to the complexity of the braking process, antilock braking system (ABS) usually face the problems such as nonlinearity, time-varying, and uncertain parameter modeling. Thus, aiming at the parameter model uncertainty problem of ABS, an adaptive neural network sliding mode controller (ADRBF-SMC) is designed in this paper. On this basis, establishing the quarter-vehicle model and the seven-degree-of-freedom vehicle model, and treating the difference between the two models as a kind of disturbance, carrying out vehicle braking performance simulation experiments to analyze the variation of braking performance parameters such as vehicle and wheel speeds, slip ratio, braking distance, braking torque, under the three cases of adaptive neural network sliding mode controller, traditional sliding mode controller, and no control. Simulation results show that the adaptive neural network sliding mode controller (ADRBF-SMC) proposed in this paper can play an effective control role in both vehicle dynamics models. In addition, the control method proposed in this paper has stronger anti-interference capability and higher robustness compared with the sliding mode controller (SMC).