A molecularly-imprinted electrochemical sensor based on a graphene–Prussian blue composite-modified glassy carbon electrode for the detection of butylated hydroxyanisole in foodstuffs

Abstract

In this study, we developed a novel molecularly-imprinted electrochemical sensor based on a glassy carbon electrode (GCE) decorated by graphene-Prussian blue (GR-PB) composites for the selective and sensitive determination of butylated hydroxyanisole (BHA). The molecularly-imprinted polymers (MIPs) were synthesized by BHA and pyrrole as the template molecule and functional monomer, respectively. Also, the MIPs were assembled on the surface of the GR-PB/GCE by electropolymerization. The sensor was characterized by cyclic voltammetry (CV), scanning electron microscopy (SEM), electrochemical impedance spectroscopy (EIS) and chronoamperometry. It was confirmed that the synergistic effects of GR and PB could improve the electrochemical response and the sensitivity of the sensor. The linear range of the sensor was from 9 × 10(-8) mol L(-1) to 7 × 10(-5) mol L(-1), with a limit of detection (LOD) of 7.63 × 10(-8) mol L(-1) (S/N = 3). The proposed sensor displayed high selectivity, excellent stability and good reproducibility for the determination of BHA. It was successfully applied to the determination of BHA in real samples.

Synthesis of graphene oxide-wrapped core–shell structured carbon sphere@Al2O3 as electrode material for voltammetric determination of butylated hydroxyanisole in food products

“…The salad dressing, potato chips, and oatmeal samples were treated according to the reported method [34]. In brief, the samples were respectively crushed using an agate mortar.…”

Recent developments, characteristics and potential applications of screen-printed electrodes in pharmaceutical and biological analysis

“…Moreover, the recent possibility of designing SPEs, including microelectrodes and chemically modified electrodes, has increased industrial and clinical interest [13][14][15][16][17][18][19][20]. SPEs combine ease of use and portability with simple and inexpensive analytical methods.…”

Molecularly imprinted polymer grafted graphene for simultaneous electrochemical sensing of 4, 4-methylene diphenylamine and aniline by differential pulse voltammetry

“…Due to its applicable to almost all of vinyl monomers with simple operation, FRP shows obvious advantages in synthesis MIPs-G [23]. The applications of MIPs-G in adsorption [24], optosensing [25] and electrochemical recognition [26][27][28][29][30] were reported.…”