A Monte Carlo approach to calculate the production prerequisites of 124I radioisotope towards the activity estimation

Abstract

The Monte Carlo simulation code MCNPX has been used to simulate the production of 124I by 124,125Te(p, xn) and 123,124Te(d,xn) reactions to form high activity 124I. For this reason, the TALYS-1.8 and ALICE/ASH codes were used to calculate the reaction cross-section. The optimal energy range of projectile is selected for this production by identifying the maximum cross-section and the minimum impurity due to other emission channels. Target geometry is designed by SRIM code based on stopping power calculations with identical dimensions as the experimental data. The thick target yield of reactions is predicted because of the excitation functions and stopping power. All of the prerequisites obtained from the above interfaces are adjusted in MCNPX code and the production process is simulated according to benchmark experiments. Thereafter, the energy distribution of proton in targets, the amount of residual nuclei during irradiation, were calculated. The results are in good agreement with the reported data, thus confirming the usefulness and accuracy of MCNPX as a tool for the optimization of other radionuclides production. Based on the results, the 124Te(p,n)124I process seems to be the most likely candidate to produce the 124I in low-energy cyclotrons.

Efficiency of 124I radioisotope production from natural and enriched tellurium dioxide using 124Te(p,xn)124I reaction

“…Thus, to obtain a close agreement between the simulated and experimental values, these processes should be taken into account. The experimental yield is also influenced by a beam profile and an intensity, the radiation damage effects and a chemical separation yield [ 57 , 59 ]. In the case of the proton beam of 15 μA, an additional source of error is the lack of repeated measurements (due to the target disruption).…”