A multicenter prospective study of patients undergoing open ventral hernia repair with intraperitoneal positioning using the&lt;br /&gt;monofilament polyester composite ventral patch: interim results of the PANACEA study

Berrevoet, Frederik; Doerhoff, Carl; Muysoms, Filip; Hopson, Steven B.; Muzi, M Gallinella; Nienhuijs, Simon W.; Kullman, Eric; Tollens, Tim; Schwartz, Mark R.; LeBlanc, Karl A.; Velanovich, Vic; Jørgensen, Lars Nannestad

doi:10.2147/mder.s132755

Cited by 12 publications

(24 citation statements)

References 30 publications

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“…In a systematic literature review 77 including both open and laparoscopic primary ventral and incisional hernia repairs, it was concluded that there was no significant association between hernia recurrence and mesh overlap for open repairs. In a prospective case series 66 that used an intraperitoneal patch, there were no differences in mesh overlap between recurrent and non-recurrent hernias. In a recent retrospective study 78 of 1558 patients with a mean follow-up of 4 years, an overlap of less than 1 cm was associated with a higher recurrence rate in univariable analysis.…”

Section: Quality Of Evidence: Strength Of Recommendation: Weakmentioning

confidence: 92%

Guidelines for treatment of umbilical and epigastric hernias from the European Hernia Society and Americas Hernia Society

Henriksen

Montgomery

Kaufmann

et al. 2020

British Journal of Surgery

227

198

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Background: Umbilical and epigastric hernia repairs are frequently performed surgical procedures with an expected low complication rate. Nevertheless, the optimal method of repair with best short-and long-term outcomes remains debatable. The aim was to develop guidelines for the treatment of umbilical and epigastric hernias. Methods: The guideline group consisted of surgeons from Europe and North America including members from the European Hernia Society and the Americas Hernia Society. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach, the Scottish Intercollegiate Guidelines Network (SIGN) critical appraisal checklists, and the Appraisal of Guidelines for Research and Evaluation (AGREE) instrument were used. A systematic literature search was done on 1 May 2018, and updated on 1 February 2019. Results: Literature reporting specifically on umbilical and epigastric hernias was limited in quantity and quality, resulting in a majority of the recommendations being graded as weak, based on low-quality evidence. The main recommendation was to use mesh for repair of umbilical and epigastric hernias to reduce the recurrence rate. Most umbilical and epigastric hernias may be repaired by an open approach with a preperitoneal flat mesh. A laparoscopic approach may be considered if the hernia defect is large, or if the patient has an increased risk of wound morbidity. Conclusion: This is the first European and American guideline on the treatment of umbilical and epigastric hernias. It is recommended that symptomatic umbilical and epigastric hernias are repaired by an open approach with a preperitoneal flat mesh.

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Section: Quality Of Evidence: Strength Of Recommendation: Weakmentioning

confidence: 92%

Guidelines for treatment of umbilical and epigastric hernias from the European Hernia Society and Americas Hernia Society

Henriksen

Montgomery

Kaufmann

et al. 2020

British Journal of Surgery

227

198

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“…These complications are probably due to excessive traction on the straps in order to align the patch flatly against the parietal peritoneum [4, 7]. Although mesh misalignment may also have occurred in this series [8], as laparoscopic evaluation is the only way to verify this, the low recurrence (3%) and reoperation rate observed at the end of the 2 year follow up, show that at least the clinical impact of misalignment has been minimal. Nevertheless, accurate surgical technique with complete dissection of the falciform ligament cranially and the umbilical folds caudally is mandatory to obtain best patient outcomes, especially when using the largest 8.6 cm patch.…”

Section: Discussionmentioning

confidence: 95%

“…As reported in the early results of this prospective multicenter cohort study, patients underwent a small primary ventral hernia repair using the Parietex™ Composite Ventral Patch (PCO-VP) (Medtronic; Trevoux, France) with a diameter of 4.6, 6.6, or 8.6 cm, depending on the size of the defect [8]. The objectives were to assess hernia recurrence at 24 months follow-up and safety.…”

Section: Methodsmentioning

confidence: 99%

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Open ventral hernia repair with a composite ventral patch - final results of a multicenter prospective study

Berrevoet

Doerhoff²,

Muysoms

et al. 2019

BMC Surg

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Background This study assessed clinical outcomes, including safety and recurrence, from the two-year follow-up of patients who underwent open ventral primary hernia repair with the use of the Parietex™ Composite Ventral Patch (PCO-VP). Methods A prospective single-arm, multicenter study of 126 patients undergoing open ventral hernia repair for umbilical and epigastric hernias with the PCO-VP was performed. Results One hundred twenty-six subjects (110 with umbilical hernia and 16 with epigastric hernia) with a mean hernia diameter of 1.8 cm (0.4–4.0) were treated with PCO-VP. One hundred subjects completed the two-year study. Cumulative hernia recurrence was 3.0% (3/101; 95%CI: 0.0–6.3%) within 24 months. Median Numeric Rating Scale pain scores improved from 2 [0–10] at baseline to 0 [0–3] at 1 month ( P < 0.001) and remained low at 24 months 0 [0–6] ( P < 0.001). 99% (102/103) of the patients were satisfied with their repair at 24 months postoperative. Conclusions The use of PCO-VP to repair primary umbilical and epigastric defects yielded a low recurrence rate, low postoperative and chronic pain, and high satisfaction ratings, confirming that PCO-VP is effective for small ventral hernia repair in the two-year term after implantation. Trial registration The study was registered publically at clinicaltrials.gov ( NCT01848184 registered May 7, 2013).

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“…In a multicenter prospective study, Berrevoet et al assessed surgeon satisfaction related to ease of mesh use in 95% of surgeries and reported an average surgical time of 36.2 minutes, favoring the open ventral patch technique. 14 Both surgical procedures represent minimally invasive techniques, therefore early mobilization of the patients is characteristic for these type of interventions. Vychnevskaia et al and Vorst et al highlighted the benefits of minimally invasive procedures.…”

Section: Primary Considerationsmentioning

confidence: 99%

Proper Surgical Treatment of Small and Medium Size Umbilical Hernias. A Single Surgeon Experience

Élthes

Sala

Neagoe

et al. 2020

Journal of Interdisciplinary Medicine

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AbstractIntroduction: Minimally invasive surgical procedures have become routine interventions nowadays and represent an effective therapeutic option even for small umbilical hernias, providing favorable postoperative and aesthetic results.Aim of study: To determine the most appropriate minimally invasive treatment option for small and medium size umbilical hernias.Materials and methods: We conducted a prospective study on 50 patients with small or medium umbilical hernia (<4 cm). All patients benefited of minimal invasive surgery with mesh implantation. Depending on the surgical procedure, two major groups were defined: group A – patients with open surgical approach (n = 24) and group B – patients undergoing laparoscopic surgery (n = 26). Clinical, surgical, postoperative, and follow-up data were analyzed.Results: Mesh replacement via open approach through the umbilicus was associated with significantly reduced surgical time (p = 0.0359), administration of painkillers (p = 0.0461), and use of anticoagulants (p = 0.0404). Hospital stays (p = 0.0001) and costs (p = 0.0005) were also significantly lower in this group. After 6 months of follow-up, no recurrence was observed, and no significant differences were detected regarding postoperative pain and the patients’ professional reintegration. Patient satisfaction regarding postoperative scar was superior in the open group.Conclusion: The present study indicates that the ventral patch technique is a safe and effective method for the treatment of small and medium size umbilical hernias.

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A multicenter prospective study of patients undergoing open ventral hernia repair with intraperitoneal positioning using the<br />monofilament polyester composite ventral patch: interim results of the PANACEA study

Cited by 12 publications

References 30 publications

Guidelines for treatment of umbilical and epigastric hernias from the European Hernia Society and Americas Hernia Society

Guidelines for treatment of umbilical and epigastric hernias from the European Hernia Society and Americas Hernia Society

Open ventral hernia repair with a composite ventral patch - final results of a multicenter prospective study

Proper Surgical Treatment of Small and Medium Size Umbilical Hernias. A Single Surgeon Experience

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