A Multicenter Study of the Light Visor for Seasonal Affective Disorder: No Difference in Efficacy Found Between Two Different Intensities

Rosenthal, Norman E.; Moul, Douglas E.; Hellekson, Carla; Oren, Dan A.; Frank, Arlene; Brainard, George C.; Murray, Megan G.; Wehr, Thomas A.

doi:10.1038/npp.1993.17

Cited by 62 publications

(34 citation statements)

References 7 publications

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“…For example, the incidence of SAD in latitudes of [45][46][47][48][49][50] o or higher is over 10% compared to latitudes lower than 30 o , where the prevalence is around 1%. 42 As in atypical depression of those who have SAD, 60% to 90% are women, and it occurs more frequently in younger people, often beginning when the person is at his/her twenties. 43 Many of the symptoms of winter depression (e.g.…”

Section: Seasonal Affective Disorders (Sad)mentioning

confidence: 99%

Superposição entre depressão atípica, doença afetiva sazonal e síndrome da fadiga crônica

Juruena

Cleare

2007

Rev. Bras. Psiquiatr.

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Overlap between atypical depression, seasonal affective disorder and chronic fatigue syndrome Superposição entre depressão atípica, doença afetiva sazonal e síndrome da fadiga crônica A b s t r a c t Objective: We reviewed previous studies that have described an association between abnormal functioning of the hypothalamicpituitary-adrenal axis and depression. In addition to melancholic depression, a spectrum of conditions may be associated with increased and prolonged activation of the hypothalamic-pituitary-adrenal axis. In contrast another group of states is characterized by hypoactivation of the stress system, rather than sustained activation, in which chronically reduced secretion of corticotropin releasing factor may result in pathological hypoarousal and an enhanced hypothalamic-pituitary-adrenal negative feedback. Patients with atypical depression, seasonal affective disorder and chronic fatigue syndrome fall in this category. Method: The literature data on the overlap between the key-words were reviewed, summarized and discussed. Results: Many studies suggest that these conditions themselves overlap biologically, showing hypofunction of central corticotropin releasing factor neuronal systems. Conclusions: Therefore, in the real world of clinical practice, patients often present in a grey area between classical idiopathic fatigue and early chronic atypical depression and/or seasonal depression. This underscores the potential common biological links underpinning commom symptom clusters not only between depression (atypical and seasonal) and chronic fatigue syndrome, but also other conditions characterized by in the hypothalamic-pituitary-adrenal axis mainly diminished the corticotropin realising factor activity.Descriptors: Melancholic depression; Seasonal affective disorder; Fatigue syndrome, chronic; Hypothalamus-hypophyseal system; Corticotropin releasing factor Resumo Objetivo: Foram revisados estudos que descrevem que as alterações na função do eixo hipotálamo-pituitária-adrenal e são relacionadas com o estado psicopatológico em depressão. Além da depressão melancólica, uma série de condições podem ser associadas à hiperativação prolongada do eixo hipotálamo-pituitária-adrenal. Um outro grupo de psicopatologias é caracterizado por hipoativação do mesmo eixo com redução crônica na secreção do fator de liberação de corticotrofina. Pacientes com depressão atípica, doença afetiva sazonal e síndrome da fadiga crônica estão inclusos nesta categoria. Método: Foram revisados os dados da literatura que incluem a interseção entre estes descritores, resumidos e discutidos os principais e recentes achados. Resultados: Muitos estudos têm enfatizado que estes quadros se sobrepõem biologicamente, demonstrando hipofunção no sistema relacionado ao fator de liberação de corticotrofina. Conclusões: Na prática clínica, os pacientes frequentemente se apresentam de forma intermediária entre a fadiga e a depressão atípica crônica e/ou a depressão sazonal. Isto enfatiza o potencial biológico comum que fundamenta o grupo de s...

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Section: Seasonal Affective Disorders (Sad)mentioning

confidence: 99%

Superposição entre depressão atípica, doença afetiva sazonal e síndrome da fadiga crônica

Juruena

Cleare

2007

Rev. Bras. Psiquiatr.

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“…Because not all research supports morning light therapy over evening or dual morning-evening administration, Rosenthal et al (1993) suggested that light therapy may be important because it increases the overall number of photons reaching the retina. The essence of the photon-count hypothesis is that shorter photoperiods and/or less intense light in the winter result in an insufficient dose of light (i.e., fewer photons) to the retina in SAD-vulnerable individuals (Rosenthal et al, 1993).…”

Section: Light Therapy and The Photon-counting Hypothesismentioning

confidence: 99%

“…The essence of the photon-count hypothesis is that shorter photoperiods and/or less intense light in the winter result in an insufficient dose of light (i.e., fewer photons) to the retina in SAD-vulnerable individuals (Rosenthal et al, 1993).…”

Section: Light Therapy and The Photon-counting Hypothesismentioning

confidence: 99%

Melanopsin Polymorphisms in Seasonal Affective Disorder

Roecklein¹

2005

PsycEXTRA Dataset

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“…It may be that the methodology of these two studies has resulted in an inflated figure as both defined cases using the seasonality score on the Seasonal Pattern Assessment Questionnaire (SPAQ; Rosenthal et al, 1984)rather than DSM criteria. The SPAQhas also been used to demonstrate that in the USA prevalence of SAD rises with increasing latitude, which supports the hypothesis that environmental light conditions are important in its aetiology (Rosen et al, 1990).…”

Section: Epidemiologymentioning

confidence: 99%

“…Clinical assessment may be augmented by use of the SPAQ (Rosenthal et al, 1984). This is a self-rated questionnaire which assesses the degree of seasonal variation of mood symptoms and determines at which time of year symptoms are at their worst.…”

Section: Clinical Assessmentmentioning

confidence: 99%

Seasonal affective disorder

Rodin¹,

Thompson²

1997

Adv. psychiatr. treat

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Seasonal affective disorder (SAD) is a recurrent depressive disorder in which episodes occur at a particular time of year. The most frequent variant is winter SAD in which patients become depressed during the autumn or early winter, with remission or conversion to hypomania the following spring. Recognition of winter SAD is important because the diagnosis predicts a good response to the novel treatment of phototherapy. One other variant, summer SAD, has also been described and we will discuss this condition separately. Otherwise, we will confine our discussion to the winter variant which we will refer to as SAD.

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A Multicenter Study of the Light Visor for Seasonal Affective Disorder: No Difference in Efficacy Found Between Two Different Intensities

Cited by 62 publications

References 7 publications

Superposição entre depressão atípica, doença afetiva sazonal e síndrome da fadiga crônica

Superposição entre depressão atípica, doença afetiva sazonal e síndrome da fadiga crônica

Melanopsin Polymorphisms in Seasonal Affective Disorder

Seasonal affective disorder

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