A multifunctional BODIPY based fluorescent probe for hydrogen sulfide detection and photodynamic anticancer therapy in HCT116 colon cancer cell

The Role of Hitchhiking in Cancer Therapeutics—A Review

“…Furthermore, because of its noninvasiveness and spatiotemporal agility, PDT has gathered interest in cancer therapy. [121] Nearinfrared (NIR) absorption (>600 nm) is one of the prerequisites for an "optimal" PS in PDT. [122] Typical NIR PSs are quite hydrophobic and thus readily congregate in aqueous conditions.…”

A fast-responsive fluorescent probe based on a styrylcoumarin dye for visualizing hydrogen sulfide in living MCF-7 cells and zebrafish

“…HRMS (high-resolution mass spectroscopy) analysis was carried out using AB Sciex TripleTOF 4600 apparatus. 1 H-and 13 C-NMR (nuclear magnetic resonance) spectra were obtained using a Bruker Avance 600 MHz spectrometer. The UV-vis absorption and uorescence spectra data were obtained using a Shimadzu UV-2450 spectrometer and HITACHI F-4600 uorescence spectrophotometer.…”

“…1 H NMR (600 MHz, DMSO) d (ppm) 10.58 (s, 1H), 8.67 (s, 1H), 8.18 (dd, J ¼ 41.8, 8.2 Hz, 2H), 7.96-7.63 (m, 5H), 7.50 (t, J ¼ 7.6 Hz, 1H), 7.27 (t, J ¼ 7.4 Hz, 1H), 6.87 (dd, J ¼ 8.7, 1.8 Hz, 1H), 6.77 (d, J ¼ 1.8 Hz, 1H), 6.58 (s, 1H), 4.48 (q, J ¼ 7.0 Hz, 2H), 1.34 (t, J ¼ 7.1 Hz, 3H). 13…”

“…This is associated with many illnesses, such as diabetes, mental decline, cardiovascular diseases, and cancer. [10][11][12][13] Therefore, the accurate measurement of H 2 S in organisms and the environment is of great signicance for in-depth studies on the pathogenesis of related diseases.…”

Turn-on silicon-based fluorescent probe for visualizing endogenous CO during hypoxia

“…Fluorescent probes have the ability to quickly enter cells in a non-invasive manner, have high sensitivity and excellent photostability, and have become one of the main methods for studying biological processes. [32][33][34][35] The Tsuji-Trost reaction using CO reduction has always been the main design idea behind CO florescent probes responding to CO. [36][37][38][39][40][41][42][43][44][45][46] For example, Feng's group designed a fluorescent probe that uses allyl chloroformate to protect its amino group and restores fluorescence by reducing Pd 2+ with CO. 47 As a heavy metal element, palladium is inevitably toxic to organisms, which is not conducive to the visualization and tracking of endogenous CO. The critical issue for this target is the lack of related CO probe design strategies.…”