A multifunctional nanocatalyst based on ultra-fluorescent carbon quantum dots for cascade enzymatic activity and stimuli-responsive chemotherapy of cancer

Preclinical Assessment of Enhanced Chemodynamic Therapy by an FeMnOx-Based Nanocarrier: Tumor-Microenvironment-Mediated Fenton Reaction and ROS-Induced Chemotherapeutic for Boosted Antitumor Activity

“…The capability of FeMnO x NPs to reduce GSH concentration was quantified using Ellman’s confirmatory probe. , The existence of Fe 3+ /Mn 4+ ions allows them to react with GSH and transform into GSSG, intermediates that produce an absorbance peak at nearly 412 nm. A solution consisting of 50 μL of GSH (1 mM) and 250 μL of different FeMnO x NPs was prepared in PBS (5.0) to evaluate this concept.…”

Strategic Assessment of Boron-Enriched Carbon Dots/Naproxen: Diagnostic, Toxicity, and In Vivo Therapeutic Evaluation

“…Naproxen Kinetical Release Assessment. Following our prior reports protocols, 37,38 the drug release experiments for naproxen were conducted under different pH conditions (pH 4, 7, and 9) using 250 mL of PBS. Briefly, 5 mL of B-CDs/ Naproxen (200 ppm) was sealed in a dialysis bag (MWCO 1000 Da), immersed in PBS, and dialyzed for 24 h under fixed conditions (300 rpm at room temperature).…”

Chemodynamic PtMn Nanocubes for Effective Photothermal ROS Storm a Key Anti-Tumor Therapy in-vivo

“…Significantly, with the continuous development of nanotechnology, more and more nanomaterials are being applied to cancer research. [11][12][13][14][15][16][17][18][19] Using nanomaterials as carriers, biomaterials with specific structure and function can be designed and engineered specifically for tumor cells, the tumor microenvironment (TME), and the immune system to overcome toxicity and improve drug capacity and bioavailability. [20][21][22][23][24][25][26][27][28] Thus, the development of effective and safe cancer treatments has become a hot research topic.…”