A multifunctional nanocomposite of magnetic γ-Fe2O3 and mesoporous fluorescent ZnO

Mukhopadhyay, Soumita; Mohanta, Subas Chandra; Saha, Arindam; Devi, P. Sujatha

doi:10.1016/j.jallcom.2015.08.230

Cited by 16 publications

(3 citation statements)

References 38 publications

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“…Tumors develop rapidly, accumulating lactic acid and lowering the pH of these areas (pH 4–6) in comparison to physiological status (pH 7.4) [ 50 , 60 ]. The highly expanded surface area, appropriate porosity, and capacity to be coated by polymers as core-shell nanoparticles make Fe 2 O 3 NPs such an ideal carrier for pH-responsive drug delivery platforms, moreover, there is a potential for the reduction of Fe 2 O 3 based nanocarriers for loading biomolecules ( Figure 2 ) [ 61 , 62 , 63 , 64 , 65 , 66 ]. These characteristics provide sufficient room for loading antitumor medications.…”

Section: Drug Delivery Application Of Fe 2 O ...mentioning

confidence: 99%

“…They observed that total discharges were 32 and 63% at pH levels of 7.2 and 5.5, respectively. Daunorubicin hydrochloride was loaded into a γ-Fe 2 O 3 /ZnO nanocomposite by Maiti et al [ 63 ], and then drug delivery was measured at pH 5.5 and 7.5. When used as a model for tumor locations, the acidic setting aided in the drug delivery.…”

Section: Drug Delivery Application Of Fe 2 O ...mentioning

confidence: 99%

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Role of Iron Oxide (Fe2O3) Nanocomposites in Advanced Biomedical Applications: A State-of-the-Art Review

et al. 2022

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Nanomaterials have demonstrated a wide range of applications and recently, novel biomedical studies are devoted to improving the functionality and effectivity of traditional and unmodified systems, either drug carriers and common scaffolds for tissue engineering or advanced hydrogels for wound healing purposes. In this regard, metal oxide nanoparticles show great potential as versatile tools in biomedical science. In particular, iron oxide nanoparticles with different shape and sizes hold outstanding physiochemical characteristics, such as high specific area and porous structure that make them idoneous nanomaterials to be used in diverse aspects of medicine and biological systems. Moreover, due to the high thermal stability and mechanical strength of Fe2O3, they have been combined with several polymers and employed for various nano-treatments for specific human diseases. This review is focused on summarizing the applications of Fe2O3-based nanocomposites in the biomedical field, including nanocarriers for drug delivery, tissue engineering, and wound healing. Additionally, their structure, magnetic properties, biocompatibility, and toxicity will be discussed.

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Section: Drug Delivery Application Of Fe 2 O ...mentioning

confidence: 99%

Section: Drug Delivery Application Of Fe 2 O ...mentioning

confidence: 99%

Role of Iron Oxide (Fe2O3) Nanocomposites in Advanced Biomedical Applications: A State-of-the-Art Review

et al. 2022

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“…Figure a–b show the representative TEM images of IONF_250, revealing the well‐defined flake‐like structure with mesopores. Furthermore, clear lattice fringes with a d ‐spacing of 0.25 nm were observed in the high‐resolution TEM (HRTEM) image of IONF_250, indexed to the d ‐spacing of (311) plane of γ‐Fe 2 O 3 (Figure c) ,. In addition, the presence of pores on the IONF can also be observed from this HRTEM image, which originated from the decomposition of organic constituents.…”

Section: Resultsmentioning

confidence: 81%

Enhanced Peroxidase Mimetic Activity of Porous Iron Oxide Nanoflakes

et al. 2019

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Porous nanomaterials with superior peroxidase mimetic activity (nanozyme) at room temperature have gained increasing attention as potential alternatives to natural peroxidase enzymes. Herein, we report the application of porous iron oxide nanoflakes (IONFs), synthesized using the combination of solvothermal method and high-temperature calcination as peroxidase nanozyme for the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) in the presence of H 2 O 2 . The four IONF catalysts possess porous structures with a wide pore size distribution between 2-30 nm and high specific surface areas around to 200 m 2 g À1 . The increase of calcination temperature of the IONFs from 250 8C to 400 8C resulted in a gradual decrease in their specific surface area and Michaelis-Menten constant (K m ) for TMB oxidation. The optimum IONF sample showed a much lower K m at 0.24 mM (towards TMB) compared to natural enzyme horseradish peroxidase (HRP) at 0.434 mM, revealing the promising potential of the asprepared IONFs as alternatives to HRP for biosensing applications.[a] Dr.

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ChemInform Abstract: A Multifunctional Nanocomposite of Magnetic γ‐Fe₂O₃ and Mesoporous Fluorescent ZnO.

et al. 2015

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A Multifunctional Nanocomposite of Magnetic -Fe 2O3 and Mesoporous Fluorescent ZnO. -The title nanocomposite is prepared by dispersing -Fe 2O3 and mesoporous ZnO in EtOH under sonication (250 W, 10 min) before mixing and refluxing (80 C, 4 h). Drug conjugation by ultrasonication and release characteristics of the title nanocomposite reveal that mesoporous ZnO takes up 86% of the anticancer drug daunorubicin hydrochloride within 60 min and that the -Fe 2O3 helps in separating the drug carrier from solution. Drug loading hereby is monitored by the change in adsorbance of the drug solution at 483 nm via a UV/vis spectrophotometer. Release of the drug with and without ultrasonic irradiation indicates that in both cases the amount is higher under acidic pH. The presence of a high saturation magnetization along with visible emission makes this composite an ideal multifunctional material for drug delivery studies. -(MAITI, D.; MUKHOPADHYAY, S.; CHANDRA MOHANTA, S.; SAHA, A.; SUJATHA DEVI*, P.; J. Alloys Compd. 653 (2015) 187-194, http://dx.

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A multifunctional nanocomposite of magnetic γ-Fe2O3 and mesoporous fluorescent ZnO

Cited by 16 publications

References 38 publications

Role of Iron Oxide (Fe2O3) Nanocomposites in Advanced Biomedical Applications: A State-of-the-Art Review

Role of Iron Oxide (Fe2O3) Nanocomposites in Advanced Biomedical Applications: A State-of-the-Art Review

Enhanced Peroxidase Mimetic Activity of Porous Iron Oxide Nanoflakes

ChemInform Abstract: A Multifunctional Nanocomposite of Magnetic γ‐Fe₂O₃ and Mesoporous Fluorescent ZnO.

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A multifunctional nanocomposite of magnetic γ-Fe2O3 and mesoporous fluorescent ZnO

Cited by 16 publications

References 38 publications

Role of Iron Oxide (Fe2O3) Nanocomposites in Advanced Biomedical Applications: A State-of-the-Art Review

Role of Iron Oxide (Fe2O3) Nanocomposites in Advanced Biomedical Applications: A State-of-the-Art Review

Enhanced Peroxidase Mimetic Activity of Porous Iron Oxide Nanoflakes

ChemInform Abstract: A Multifunctional Nanocomposite of Magnetic γ‐Fe2O3 and Mesoporous Fluorescent ZnO.

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ChemInform Abstract: A Multifunctional Nanocomposite of Magnetic γ‐Fe₂O₃ and Mesoporous Fluorescent ZnO.