A new allenic Pauson-Khand cycloaddition for the preparation of α-methylene cyclopentenones

Effect of Varying the Anionic Component of a Copper(I) Catalyst on Homologation of Arylacetylenes to Allenes by the Mannich Reaction

“…For instance, allenes participate in a variety of cycloaddition and electrocyclic reactions affording products such as sterpurenes that are not easily accessible by other synthetic methods. [2,3] In addition, the allene moiety can be transformed into a variety of other functional groups such as olefins, α,β-unsaturated carbonyl compounds and alkynes. [4] Moreover, allene axial chirality has been used to transfer asymmetry in cycloaddition reactions.…”

A DFT‐Based Theoretical Investigation of the Mechanism of the PtCl2‐Mediated Cycloisomerization of Allenynes

“…Additionally, it has been reported that allenynes can exhibit different modes of cyclization depending on the metallic catalyst: Pd complexes catalyze cyclization of 1,7‐allenynes to six‐membered carbocyles, whereas Rh complexes afford five‐membered rings 6. Interestingly, in spite of this and related efforts on this subject,7–11 it was only very recently that Brummond et al established that substitution of the allene has an influence on the regiochemical course of this reaction 12…”

Stoichiometric applications of organotransition metal complexes in organic synthesis

“…In the first, the scope of the olefin that can be used in the Pauson-Khand reaction is extended to include electron deficient alkenes, by increasing the equivalents of alkene that are vein, it has now been found that allenes are suitable olefinic partners for this reaction, provided that the Pauson-Khand reaction is performed in an intramolecular sense. 77 In a similar…”