A New Approach for Decreasing Postoperative Peritoneal Adhesions: Preventing Peritoneal Trauma with Soybean Oil

Abstract

Soybean oil can effectively decrease adhesion formation if applied before peritoneal trauma.

Anti-adhesive effects of argan oil on postoperative peritoneal adhesions

“…Additionaly the anti-inflammatory effect of fatty acids, Jiang et al reported that γ-tocopherol inhibits proinflammatory PGE2 and LTB4, decreases TNF-alpha, and γ-tocopherol shows antiinflammatory effect [7][8][9][10][11]22]. Giant cells are seen in granulamatous inflammation that is different patern of chronic inflammatory reaction and generally occurs due to foreign bodies [9,10].…”

“…Argan oil reduced adhesion formation with its liquid form like as soybean oil, olive oil, omega 3 fatty acids [7][8][9][10][11].…”

“…Barriers, surgical or non invasive strategies, cellular strategies, drugs and agents have been used at clinical or experimental studies [6]. Fatty acids contents such as soybean oil, ClinOleic, canola oil, omega 3 fatty acids and olive oil were studied for prevention of PPA experimentally in literature [7][8][9][10][11].…”

The protective effect of ClinOleic against post-surgical adhesions

“…[30][31][32] Aysan et al performed many different studies regarding the prevention of peritoneal adhesions. These included using soybean oil [14] before peritoneal trauma, using honey, which has a dense and complex chemical composition, [33] and using viscous 6% hydroxy ethyl starch (HES) solution. [34] When the viscosity of the fluid inserted into the intraperitoneal cavity was increased, the reduction of intra-abdominal adhesion formation was achieved by an unknown viscosity-dependent process.…”

“…Many soy ingredients have potential health benefits for patients. [14,15] Olive oil has long been recognized for its unusual fat content. This plant oil is one of the few widely used culinary oils that contain approximately 75% oleic acid (a monounsaturated, omega-9 fatty acid) and 21% linoleic and linolenic acid.…”